THE TROMSO HEART-STUDY - DISTRIBUTION OF, AND DETERMINANTS FOR, GAMMA-GLUTAMYL-TRANSFERASE IN A FREE-LIVING POPULATION
THE TROMSO HEART-STUDY - DISTRIBUTION OF, AND DETERMINANTS FOR, GAMMA-GLUTAMYL-TRANSFERASE IN A FREE-LIVING POPULATION
复制标题
DOI：
10.3109/00365518609086483
复制
发表时间：
1986-02-01
影响因子：
2.1
通讯作者：
TRY, K
中科院分区：
文献类型：
--
作者：
ARNESEN, E;HUSEBY, NE;TRY, K
对1579名年龄在20-54岁的男性和1654名年龄在20-49岁的女性进行了γ -谷氨酰转移酶（GGT）检测，以筛查冠状动脉危险因素。该分布呈右偏，男性和女性的中位数分别为15和10 U/l。不到3.8%的男性和0.8%的女性患有GGT。50 U / l。在挪威，低水平的GGT与肝硬化的低死亡率和适度饮酒相匹配。对每个性别的多元回归分析显示，体重指数、饮酒和喝咖啡之间存在强烈的正相关关系，而血清甘油三酯和距离最后一餐的时间之间存在较弱的正相关关系。在妇女中，口服避孕药的使用与GGT呈正相关。
Gamma-glutamyltransferase (GGT) was measured in 1579 men, aged 20-54 years, and 1654 women, aged 20-49 years, screened for coronary risk factors. The distribution was right-skewed with medians 15 and 10 U/l for men and women, respectively. Less than 3.8% of the men and 0.8% of the women had GGT .gtoreq. 50 U/l. The low level of GGT matched well with the low mortality of cirrhosis and the modest use of alcohol in Norway. Multiple regression analysis for each sex showed a strong positive association with body mass index, use of alcohol and, unexpectedly, a negative association with coffee consumption, whereas serum triglycerides and the time since the last meal showed a weaker positive association. In women, use of oral contraceptives was positively associated with GGT.