Cerebral hemodynamics in angioma patients: an intraoperative study.
Cerebral hemodynamics in angioma patients: an intraoperative study.
复制标题
血管瘤患者的脑血流动力学：一项术中研究。
DOI：
10.3171/jns.1987.67.6.0822
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发表时间：
1987
影响因子：
4.1
通讯作者：
Helmuth Steinmetz
中科院分区：
文献类型：
--
作者：
W. Hassler;Helmuth Steinmetz
对33例脑动静脉畸形(AVM)手术中的局部血流动力学进行了观察。在所有病例中，使用微血管多普勒超声测量血流速度和对二氧化碳变化的血管运动反应性。对6例患者进行了血管内压记录。血管内压低，血流速度快，外周血流阻力低，血管运动反应性很差。远端脑动脉未见异常。供血正常脑的动静脉畸形供血动脉分支的多普勒结果显示其周围分布有小动脉扩张。在切除血管瘤后，以前供应它们的动脉恢复到正常的血管内压，而这些血管的血流速度下降到远远低于正常的水平。供应大脑的前AVM供给者的远程动脉和分支在血管瘤切除后没有表现出任何血管舒缩反应性受损的迹象。这一结果与正常灌流压突破理论相反。
Local hemodynamics were investigated during 33 operations for cerebral arteriovenous malformation (AVM). In all cases, microvascular Doppler sonography was used to measure flow velocities and vasomotor reactivity to CO2 changes. Intravascular pressure recordings were performed in six patients. The AVM feeders had low intravascular pressure, high flow velocity, low peripheral stream resistance, and very poor vasomotor reactivity. Remote brain arteries showed no abnormalities. Doppler findings in arterial branches of AVM feeders that supplied normal brain indicated arteriolar dilation in their peripheral distribution. On removal of the angiomas, the arteries that formerly supplied them showed a return to normal intravascular pressure, whereas flow velocities dropped far below normal in these vessels. Remote arteries and branches of the former AVM feeders supplying the brain did not show any signs of impaired vasomotor reactivity following angioma removal. The results are in contrast to the normal perfusion pressure breakthrough theory.