Improvement in intestinal function of hamsters as influenced by consumption of polysaccharide-rich sage weed extracts
Improvement in intestinal function of hamsters as influenced by consumption of polysaccharide-rich sage weed extracts
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DOI：
10.1016/j.foodchem.2012.02.062
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发表时间：
2012-08-15
期刊：
影响因子：
8.8
通讯作者：
Chau, Chi-Fai
中科院分区：
文献类型：
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作者：
Huang, Ya-Ling;Chau, Chi-Fai
本研究旨在探讨富含多糖的水溶性鼠尾草（Salvia plebeia）提取物对肠道功能的影响。结果表明，该提取物含有丰富的水溶性多糖（60.5/100 g提取物），主要由果胶多糖和半纤维素组成。在对照饮食中以0.5/100 g饮食的水平包含鼠尾草提取物导致显著的（P < 0.05）改善对仓鼠的肠和粪便参数的影响，例如缩短胃肠通过时间、减少盲肠氨、减少每日粪便氨排出量、增加盲肠内容物中的短链脂肪酸浓度和降低β-D-葡萄糖醛酸酶的活性，β-D-葡糖苷酶、粘蛋白酶和尿素酶。这些研究结果表明，摄入足够的鼠尾草提取物（0.5/100 g饮食）可能通过减少肠粘膜暴露于有毒物质和其他有害化合物而在维持肠道健康方面发挥作用。(C)2012爱思唯尔有限公司保留所有权利。
The purpose of this study was to investigate the effect of the water-soluble polysaccharide-rich sage weed (Salvia plebeia) extracts on intestinal function. The results showed that the extract is rich in water-soluble polysaccharides (60.5/100 g extract), which are mainly composed of pectic polysaccharides and hemicellulose. The inclusion of sage weed extract in the control diet at a level of 0.5/100 g diet resulted in significantly (P < 0.05) improved effects on intestinal and faecal parameters of the hamsters, such as shortened gastrointestinal transit time, reduced caecal ammonia, decreased daily faecal ammonia output, increased short-chain fatty acid concentrations in caecal content, and lowered activities of beta-D-glucuronidase, beta-D-glucosidase, mucinase, and urease. These findings suggest that an adequate intake of sage weed extracts (0.5/100 g diet) may play a role in the maintenance of intestinal health by reducing the exposure of intestinal mucosa to toxic materials and other harmful compounds. (C) 2012 Elsevier Ltd. All rights reserved.