VARIOUS FACTORS INFLUENCING THE SIGNAL INTENSITY OF OLIGONUCLEOTIDES IN ELECTROSPRAY MASS-SPECTROMETRY
VARIOUS FACTORS INFLUENCING THE SIGNAL INTENSITY OF OLIGONUCLEOTIDES IN ELECTROSPRAY MASS-SPECTROMETRY
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DOI：
10.1002/bms.1200230604
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发表时间：
1994-06-01
期刊：
影响因子：
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通讯作者：
BAYER, E
中科院分区：
文献类型：
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作者：
BLEICHER, K;BAYER, E
寡核苷酸的电喷雾质谱信号强度低，且易与金属离子发生团簇，影响其质谱质量。这有时使得精确测定分子质量是不可能的。我们在这里描述几个因素有助于这些影响，并显示了一些改善的手段。
The quality of electrospray mass spectra of oligonucleotides often suffers from the low signal intensity and clustering with metal ions. This sometimes makes an exact determination of the molecular masses impossible. We describe here several factors contributing to these effects and show some means for their improvement.