Relaxation dynamics of a single DNA molecule

Relaxation dynamics of a single DNA molecule
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DOI:
10.1103/physreve.71.061920
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发表时间:
2005-06-01
期刊:
影响因子:
2.4
通讯作者:
Feingold, M
Feingold, M
中科院分区:
物理与天体物理3区
文献类型:
--
作者:
Goshen, E;Zhao, WZ;Feingold, M

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研究了单个DNA分子的弛豫。该实验系统由光镊和一个微米大小的珠子组成,珠子通过一个单一的双链DNA分子拴在样品的底部。珠减慢DNA从强拉伸构型的松弛,使得其通过拉伸平衡状态。这允许的弛豫轨迹,这是在良好的协议与实验的理论描述。
The relaxation of a single DNA molecule is studied. The experimental system consists of optical tweezers and a micron-sized bead that is tethered to the bottom of the sample by a single double-stranded DNA molecule. The bead slows down the DNA relaxation from a strongly stretched configuration such that it is passing through stretched equilibrium states. This allows for a theoretical description of the relaxation trajectory, which is in good agreement with experiment.