Salt intake and body weight correlate with higher blood pressure in the very elderly population: The Sukagawa study
Salt intake and body weight correlate with higher blood pressure in the very elderly population: The Sukagawa study
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DOI：
10.1111/jch.13593
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发表时间：
2019-07-01
影响因子：
2.8
通讯作者：
Tominaga, Ryoji
中科院分区：
文献类型：
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作者：
Iida, Hidekazu;Kurita, Noriaki;Tominaga, Ryoji
由于很少有流行病学研究调查生活方式因素对高龄人群高血压的影响，我们进行了一项横断面研究，以探讨高龄人群中估计盐摄入量和体重与血压的关系。我们招募了 288 名日本福岛县须贺川市居民、75 岁或以上的参与者，他们参加了 2015 年进行的健康检查。使用田中法从现场尿液样本中估算了盐摄入量。所有参与者的年龄、估计盐摄入量和体重的平均值分别为 79.7 岁、9.1 克/天（标准偏差 2.4 克）和 54.3 公斤（标准偏差 10.2 公斤）。一般线性模型显示盐摄入量和体重与较高的收缩压 (SBP) 水平相关（每标准差较高水平，调整后的差异分别为 4.13 mm Hg [95% 置信区间 1.69-6.57] 和 5.34 mm Hg [95% 置信区间 2.12-8.56]）。体重与较高的舒张压 (DBP) 水平相关（每个标准差较高水平为 2.74 mm Hg [95% 置信区间 0.58-4.90]）。然而，盐摄入量与较高的舒张压水平无关（每个标准差较高水平为 1.15 mm Hg [95% 置信区间 -0.49 至 2.79]）。我们的研究结果表明，在老年人群中，较高的收缩压与盐摄入量和体重相关，而较高的舒张压与体重相关。这项研究为改变生活方式以预防高血压作为一种人群方法提供了理论依据。
As few epidemiological studies have investigated the effect of lifestyle factors on hypertension in the very elderly population, we conducted a cross-sectional study to examine the association of estimated salt intake and body weight with blood pressure in the very elderly population. We enrolled 288 participants aged 75 years or older who were residents of Sukagawa City, Fukushima Prefecture, Japan, who attended the health checkup conducted in 2015. Salt intake was estimated from spot urine samples using the Tanaka method. The mean values for age, estimated salt intake, and body weight of all participants were 79.7 years, 9.1 g/d (standard deviation 2.4 g), and 54.3 kg (standard deviation 10.2 kg), respectively. General linear models showed that salt intake and body weight were associated with higher systolic blood pressure (SBP) levels (per standard deviation higher level, adjusted difference 4.13 mm Hg [95% confidence interval 1.69-6.57] and 5.34 mm Hg [95% confidence interval 2.12-8.56], respectively). Body weight was associated with higher diastolic blood pressure (DBP) levels (per standard deviation higher level, 2.74 mm Hg [95% confidence interval 0.58-4.90]). However, salt intake was not associated with higher diastolic blood pressure levels (per standard deviation higher level, 1.15 mm Hg [95% confidence interval -0.49 to 2.79]). Our findings suggest that higher SBP is associated with both salt intake and body weight and that higher DBP is associated with body weight in the very elderly population. This study provides a rationale for lifestyle modifications to prevent hypertension as a population approach.