True location of deep brain stimulation electrodes differs from what is seen on postoperative magnetic resonance images: An anthropomorphic phantom study.
True location of deep brain stimulation electrodes differs from what is seen on postoperative magnetic resonance images: An anthropomorphic phantom study.
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深部脑刺激电极的真实位置与术后磁共振图像上看到的不同：一项拟人化模型研究。
DOI：
10.1109/embc48229.2022.9871619
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发表时间：
2022
期刊：
影响因子：
--
通讯作者：
Golestanirad,Laleh
中科院分区：
文献类型：
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作者：
Nuzov,NoaB;Bhusal,Bhumi;Henry,KayleeR;Jiang,Fuchang;Rosenow,Joshua;Elahi,Behzad;Golestanirad,Laleh
深部脑刺激 (DBS) 是一种针对一系列神经和精神疾病的成熟且不断发展的治疗方法。在过去的十年中，大量研究强调了电极放置对 DBS 临床结果的影响。因此，成像现在广泛用于 DBS 电极定位，尽管不同方式确定 DBS 电极真实坐标的准确性较少被探索。术后磁共振成像 (MRI) 是 DBS 电极定位的黄金标准方法，但是，导线伪影引起的几何变形可能会限制准确性。在这项工作中，我们研究了导联尖端的真实位置与根据 MRI 伪影估计的导联尖端位置之间的差异程度，具体取决于 MRI 序列参数、采集平面、相位编码方向和植入物的颅外轨迹。临床相关性 — 结果将帮助研究人员和临床医生根据术后 MRI 扫描估计 DBS 导联和触点的真实位置
Deep brain stimulation (DBS) is an established yet growing treatment for a range of neurological and psychiatric disorders. Over the last decade, numerous studies have underscored the effect of electrode placement on the clinical outcome of DBS. As a result, imaging is now extensively used for DBS electrode localization, even though the accuracy of different modalities in determining the true coordinates of DBS electrodes is less explored. Postoperative magnetic resonance imaging (MRI) is a gold standard method for DBS electrode localization, however, the geometrical distortion induced by the lead's artifact could limit the accuracy. In this work, we investigated to what degree the difference between the true location of the lead's tip and the location of the tip estimated from the MRI artifact varies depending on the MRI sequence parameters, acquisition plane, phase encoding direction, and the implant”s extracranial trajectory. Clinical Relevance— Results will help researchers and clinicians to estimate the true location of DBS leads and contacts from postoperative MRI scans