RELATIONSHIP BETWEEN CIGARETTE-SMOKING AND HISTOLOGIC TYPE OF LUNG-CANCER, WITH SPECIAL REFERENCE TO SEX DIFFERENCE
RELATIONSHIP BETWEEN CIGARETTE-SMOKING AND HISTOLOGIC TYPE OF LUNG-CANCER, WITH SPECIAL REFERENCE TO SEX DIFFERENCE
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DOI：
10.1093/jjco/18.1.3
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发表时间：
1988-03-01
影响因子：
2.4
通讯作者：
FUJIMOTO, I
中科院分区：
文献类型：
--
作者：
SOBUE, T;SUZUKI, T;FUJIMOTO, I
为了阐明吸烟与每一种肺癌组织学类型之间关系的六个差异，对1965年至1983年在大阪成人疾病中心诊断的2083名肺癌患者（1660名男性和423名女性）的吸烟史进行了分析。这些病例中预期的吸烟率是根据日本烟草和盐公共公司每年报告的普通人群中特定性别和年龄的吸烟率计算出来的。男性吸烟与鳞状细胞癌、腺癌、小细胞癌和大细胞癌的比值比分别为5.2、3.1、6.9和4.1，女性吸烟与鳞状细胞癌的比值比分别为7.2、1.8、14.4和3.8。仅在腺癌中观察到男女之间每种组织学类型的优势比有显著差异。在鳞状细胞癌中，根据位置将其分为两组来估计优势比。男性和女性在这方面没有差异。
In order to clarify six differences associated with the relationship between smoking and each histologic type of lung cancer, the smoking histories of 2,083 lung cancer patients (1,660 men and 423 women) diagnosed at the Center for Adult Diseases, Osaka, from 1965 to 1983 were analyzed. The rates expected of smokers among these cases were calculated from the sex and age specific rates of smokers in the general population, reported annually by the Japan Tobacco and Salt Public Corporation. The odds ratios for smoking were estimated to be 5.2, 3.1, 6.9 and 4.1 in men for squamous cell carcinoma, adenocarcinoma, small cell carcinoma, and large cell carcinoma, and 7.2, 1.8, 14.4 and 3.8 in women respectively. Significant differences in the odds ratios for each histologic type between men and women were observed only for adenocarcinoma. In squamous cell carcinomas, the odds ratios were estimated by dividing them into two groups according to location. No difference was found between men and women in this respect.