Development and analytical performance of tubular polymer membrane electrode based carbon dioxide catheters.
Development and analytical performance of tubular polymer membrane electrode based carbon dioxide catheters.
复制标题
基于管状聚合物膜电极的二氧化碳导管的开发和分析性能。
DOI：
10.1021/ac00295a062
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发表时间：
1986
影响因子：
7.4
通讯作者：
Meyerhoff,ME
中科院分区：
文献类型：
--
作者：
Opdycke,WN;Meyerhoff,ME
介绍了一种新型co2分压（pC02）电位传感导管的研制及其分析性能。通过利用内管式聚合物pH电极与外部透气性硅橡胶管结合，实现了独特的传感器几何形状。一旦组装好，这种柔性导管的外径为1.1毫米。当填充适当的参考溶液和内部电解液时，所得到的装置对pC02在正常和异常生理浓度范围（15-150 torr）内的变化响应迅速（< 80 s），重现性好，接近Nemstlan行为（pC02变化54-81 mV/ 10年）。内部pH电极和气体传感器的长期稳定性取决于内部参考溶液的组成。良好的稳定性（±2 mV超过45小时）是实现磷酸盐缓冲内部参考溶液。在体外血泵研究中，新型传感器在6小时内获得的连续pC02值与传统血气仪器具有良好的相关性。在狗的血管内植入传感器的初步结果表明，它们适合连续的体内监测
The development and analytical performance of a new potentlometric pC02 (partial pressure of C02) sensing catheter Is described. A uniquesensor geometry Is achieved by utilizing an Inner tubular polymer pH electrode In conjunction with an outer gas-permeable silicone rubber tube. Once as-sembled, this flexible catheter has an outer diameter of 1.1 mm. When filled with an appropriate reference solution and Internal electrolyte, the resulting device responds rapidly (< 80 s for fogs) and reproduclbly to pC02 changes In the normal and abnormal physiological concentration range (15-150 torr) with nearly Nemstlan behavior (54-81 mV/decade change In pC02). Long-term stability of the Inner pH electrode and consequently the gas sensor Is dependent on the Internal reference solution composition. Favorable stability (±2 mV over 45 h) Is achieved with a phosphate buffered Internal reference solution. Continuous pC02 values obtained with the new sensor during 6-h In vitro blood pump studies correlate well with conventional blood-gas Instruments. Preliminary results for sensors Implanted Intravascularly In a dog demonstrate their suitability for continuous In vivo monitoring of