Molecular diagnosis of cancer
Molecular diagnosis of cancer
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癌症的分子诊断
DOI：
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发表时间：
1996
期刊：
影响因子：
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通讯作者：
F. Cotter
中科院分区：
文献类型：
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作者：
F. Cotter
第一部分：血液恶性肿瘤。基因重排PCR检测儿童急性淋巴细胞白血病微小残留病。RT-PCR检测恶性血液病BCR-ABL的研究。成熟FAB- M2型急性髓系白血病的分子诊断。逆转录聚合酶链反应分析急性早幼粒细胞白血病PML/RAR-a融合基因。急性白血病11q23 MLL基因断点的RT-PCR分析聚合酶链反应检测淋巴瘤中t（14 - 18）易位。NPM-ALK逆转录-聚合酶链反应检测非霍奇金淋巴瘤t（25）易位。恶性髓系疾病5q缺失的分子诊断。基于聚合酶链反应的方法评估同种异体骨髓移植后嵌合性。第二部分：实体瘤。视网膜母细胞瘤基因突变的鉴定。Wilms肿瘤（WT1）基因突变分析。第三部分：癌症分析的一般技术。p53基因单链构象多态性突变分析。利用荧光原位杂交方法鉴定染色体异常。比较基因组杂交。细胞和组织切片的原位杂交。细胞凋亡检测的DNA分析。索引。
Part I: Hematological malignancies. PCR of Gene Rearrangements for the Detection of Minimal Residual Disease in Childhood ALL. Detection of BCR-ABL in Hematological Malignancies by RT-PCR. Molecular Diagnosis of Acute Myeloid Leukemia with Maturation FAB- Type M2. Analysis of the PML/RAR-a Fusion Gene in Acute Promyelocytic Leukemia by Reverse- Transcription Polymerase Chain Reaction. RT-PCR Analysis of Breakpoints Involving the MLL Gene Located at 11q23 in Acute Leukemia. Polymerase Chain Reaction for Detection of the t(14 18) Translocation in Lymphomas. NPM-ALK Reverse Transcriptase-Polymerase Chain Reaction Analysis for Detection of the t(2 5) Translocation of Non-Hodgkin's Lymphoma. Molecular Diagnosis of the 5q Deletion in Malignant Myeloid Disorders. Polymerase Chain Reaction Based Methods for Assessing Chimerism Following Allogeneic Bone Marrow Transplantation. Part II: Solid Tumors. Identification of Mutations in the Retinoblastoma Gene. Mutational Analysis of the Wilms Tumor (WT1) Gene. Part III: General Techniques for Cancer Analysis. Single-Strand Conformation Polymorphism Mutation Analysis of the p53 Gene. The Characterization of Chromosomal Abnormalities Using Fluorescence In Situ Hybridization Procedures. Comparative Genomic Hybridization. In Situ Hybridization of Cells and Tissue Sections. Apoptosis Detection by DNA Analysis. Index.