Hypermagnesemia induced by massive cathartic ingestion in an elderly woman without pre-existing renal dysfunction
Hypermagnesemia induced by massive cathartic ingestion in an elderly woman without pre-existing renal dysfunction
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DOI：
10.2169/internalmedicine.44.448
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发表时间：
2005-05-01
影响因子：
1.2
通讯作者：
Ikeda, T
中科院分区：
文献类型：
--
作者：
Kontani, M;Hara, A;Ikeda, T
一位76岁的女性被转介到我们的医院反应迟钝和低血压。她出现便秘，导致肠梗阻，并在前一天口服34 g柠檬酸镁（Magcolol P-（R））。患者嗜睡，血压低于50 mmHg，心电图（ECG）显示窦性停搏伴交界性逸搏心律。她的血清镁（Mg）浓度显著升高（16.6 mg/dl =13.7 mEq/l）。急诊结肠镜检查显示缺血性结肠炎。随着病情好转，她的肾功能恢复正常。因此，本病例表明，在患有胃肠道疾病的老年患者中，在没有预先存在的肾功能不全的情况下可能发生重度高镁血症。
A 76-year-old woman was referred to our hospital for unresponsiveness and hypotension. She had developed constipation that had led to ileus and had received 34 g of magnesium citrate (Magcolol P-(R)) orally the day before. She was lethargic, her blood pressure was less than 50 mmHg, and electrocardiogram (ECG) revealed sinus arrest with Junctional escape rhythm. Her serum concentration of magnesium (Mg) was markedly elevated (16.6 mg/dl =13.7 mEq/l). Emergency colonoscopy revealed ischemic colitis. As her condition ameliorated, her renal function returned to normal. Hence, the present case suggests that severe hypermagnesemia can occur in the absence of pre-existing renal dysfunction in elderly patients with gastrointestinal diseases.