Pseudoexfoliation as a risk factor for peripheral vascular disease: a case-control study
Pseudoexfoliation as a risk factor for peripheral vascular disease: a case-control study
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DOI：
10.1038/eye.2010.175
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发表时间：
2011-02-01
期刊：
影响因子：
3.9
通讯作者：
Thomas, R.
中科院分区：
文献类型：
--
作者：
Praveen, M. R.;Shah, S. K.;Thomas, R.
目的探讨老年性白内障中假性剥脱(PEX)与周围血管病变(PVD)的关系。材料与方法对160例60岁以上老年性白内障患者进行年龄匹配病例对照观察研究。将40例有PEX的受试者与120例白内障但无PEX的受试者(对照组)进行比较。记录详细的病史，包括高血压、糖尿病、脑血管中风和缺血性心脏病。采用踝臂指数(ABI)评估年龄相关性白内障患者发生PVD的危险性。彩色多普勒超声检查分别测量ABI和PVD。最小平均ABI是主要的预后指标，因为低ABI意味着较高的PVD风险。测量每个受试者的最低平均ABI。ABI比率为
Aim To determine the association between pseudoexfoliation (PEX) and peripheral vascular disease (PVD) among age-related cataract.Setting Iladevi Cataract and IOL Research Center, Ahmedabad, India.Material and methods An observational age-matched case-control study of 160 patients over 60 years of age with age-related cataract. A total of 40 subjects with PEX (cases) were compared with 120 subjects with cataract but without PEX (controls). A detailed medical history, including hypertension, diabetes mellitus, cerebrovascular stroke and ischaemic heart disease, was recorded. Ankle brachial index (ABI) was used to determine the risk of PVD among age-related cataract patients. Color Doppler imaging was performed on the brachial and dorsalis pedis artery to measure ABI and detect PVD. Least mean ABI was the main outcome measure, as low ABI indicates higher risk for PVD. The lowest mean ABI was measured for each subject. An ABI ratio of