Data management and other logistical challenges for the GEMS: the data coordinating center perspective.
Data management and other logistical challenges for the GEMS: the data coordinating center perspective.
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DOI：
10.1093/cid/cis755
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发表时间：
2012-12
期刊：
影响因子：
--
通讯作者：
Levine MM
中科院分区：
文献类型：
--
作者：
Biswas K;Carty C;Horney R;Nasrin D;Farag TH;Kotloff KL;Levine MM
合作研究项目协调中心为全球肠道多中心研究（GEMS）提供数据管理、行政和统计支持。在4个非洲国家和3个亚洲国家进行了GEMS研究，这是在5岁以下儿童中进行的最大规模的疟疾流行病学研究。鉴于各国在地理和地缘政治上的差异，集中数据管理业务的管理是一项重大挑战。收集的数据量之大，定期将数据转移到中央数据库，以及清理数据也带来了一些挑战。本文概述了数据协调中心提供的支持和研究过程中面临的挑战的细节。
The Cooperative Studies Program Coordinating Center provided the data management, administrative, and statistical support to the Global Enteric Multicenter Study (GEMS). The GEMS study, the largest epidemiological study in the diarrheal disease area among children <5 years of age, was carried out in 4 African countries and 3 Asian countries. Given the geographical and geopolitical differences among the countries, the administration of a centralized data management operation was a major challenge. The sheer volume of the data that were collected, regular transfer of the data to a centralized database, and the cleaning of the same also posed some challenges. This paper outlines the details of the support that the data coordinating center provided and the challenges faced during the course of the study.