Timing of Transfer and Mortality in Neonates with Hypoplastic Left Heart Syndrome in California.
Timing of Transfer and Mortality in Neonates with Hypoplastic Left Heart Syndrome in California.
复制标题
在加利福尼亚州患有左心脏综合症的新生儿转移和死亡的时间。
DOI：
10.1007/s00246-021-02561-w
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发表时间：
2021-04
影响因子：
1.6
通讯作者：
Carmichael SL
中科院分区：
文献类型：
--
作者：
Purkey NJ;Ma C;Lee HC;Hintz SR;Shaw GM;McElhinney DB;Carmichael SL
Maternal race/ethnicity is associated with mortality in neonates with hypoplastic left heart syndrome (HLHS). We investigated whether maternal race/ethnicity and other sociodemographic factors affect timing of transfer after birth and whether timing of transfer impacts mortality in infants with HLHS. We linked two statewide databases, the California Perinatal Quality Care Collaborative and records from the Office of Statewide Health Planning and Development, to identify cases of HLHS born between 1/1/06 and 12/31/11. Cases were divided into three groups: birth at destination hospital, transfer on day of life 0–1 (“early transfer”), or transfer on day of life ≥ 2 (“late transfer”). We used log-binomial regression models to estimate relative risks (RR) for timing of transfer and Cox proportional hazard models to estimate hazard ratios (HR) for mortality. We excluded infants who died within 60 days of life without intervention from the main analyses of timing of transfer, since intervention may not have been planned in these infants. Of 556 cases, 107 died without intervention (19%) and another 52 (9%) died within 28 days. Of the 449 included in analyses of timing of transfer, 28% were born at the destination hospital, 49% were transferred early, and 23% were transferred late. Late transfer was more likely for infants of low birthweight (RR 1.74) and infants born to US-born Hispanic (RR 1.69) and black (RR 2.45) mothers. Low birthweight (HR 1.50), low 5-min Apgar score (HR 4.69), and the presence of other major congenital anomalies (HR 3.41), but not timing of transfer, predicted neonatal mortality. Late transfer was more likely in neonates born to US-born Hispanic and black mothers but was not associated with higher mortality. The online version of this article (10.1007/s00246-021-02561-w) contains supplementary material, which is available to authorized users.
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影响因子：
12.7
作者：
Kucik JE;Nembhard WN;Donohue P;Devine O;Wang Y;Minkovitz CS;Burke T
通讯作者：
Burke T
影响因子：
8
作者：
Bennett, Tellen D.;Klein, Matthew B.;Rivara, Frederick P.
通讯作者：
Rivara, Frederick P.
影响因子：
1.6
作者：
Egbe, Alexander;Uppu, Santosh;Srivastava, Shubhika
通讯作者：
Srivastava, Shubhika
DOI：
10.1016/j.jtcvs.2012.04.028
发表时间：
2012-10-01
影响因子：
6
作者：
Ohye, Richard G.;Schonbeck, Julie V.;Pearson, Gail D.
通讯作者：
Pearson, Gail D.
DOI：
10.1016/j.jtcvs.2014.07.094
发表时间：
2015-01-01
影响因子：
6
作者：
Anderson, Brett R.;Ciarleglio, Adam J.;Bacha, Emile A.
通讯作者：
Bacha, Emile A.