Light therapy for depression: present status, problems, and perspectives.
Light therapy for depression: present status, problems, and perspectives.
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抑郁症的光疗法：现状、问题和观点。
DOI：
10.1159/000285145
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发表时间：
1986
期刊：
影响因子：
3.6
通讯作者：
A. Wirz
中科院分区：
文献类型：
--
作者：
A. Wirz
明亮的白光（WL）改善季节性情感障碍（SAD）的抑郁症状。不同的给药方案是有效的：延长光周期（黎明和黄昏时3、2或1小时）；只在早晨（2、1或1/2小时）；只在中午（4或2小时）；只有晚上（5或2小时）。深夜的WL可能是有害的。WL的安慰剂效应尚未得到充分解决。只有SAD患者而非重度抑郁症患者对WL有反应。WL的作用机制尚不清楚，但褪黑素似乎不起主要作用。
Bright white light (WL) improves depressive symptomatology in seasonal affective disorders (SAD). Different dosage regimens are effective: photoperiod extension (3, 2, or 1 hr WL at dawn and dusk); morning only (2, 1, or 1/2 hr); midday only (4 or 2 hr); and evening only (5 or 2 hr). Late evening WL may be deleterious. The placebo effect of WL has not yet been adequately resolved. Only SAD patients and not major depressive disorders have responded to WL. The mechanism of action of WL is unknown: however melatonin does not appear to play a major role.