Multicellular stalk-like structures in Saccharomyces cerevisiae
Multicellular stalk-like structures in Saccharomyces cerevisiae
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DOI：
10.1128/jb.180.15.3992-3996.1998
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发表时间：
1998-08-01
影响因子：
3.2
通讯作者：
Fink, GR
中科院分区：
文献类型：
--
作者：
Engelberg, D;Mimran, A;Fink, GR
茎的形成是一种新的多细胞组织模式。在紫外线照射下存活的酵母细胞形成菌落，这些菌落垂直生长以形成非常长（0.5至3.0 cm）和薄（直径0.5至4 mm）的多细胞结构。我们描述了获得这些茎状结构可重复大量所需的条件。酵母突变体，突变控制细胞极性，发育过程，紫外线响应，和信号转导级联进行了测试，发现能够形成茎状结构。我们提出了一个模型，解释了机械环境力的茎形成的机制。我们发现，其他微生物（白色念珠菌，裂殖酵母，和大肠杆菌）也形成秸秆，这表明产生秸秆的能力可能是微生物的一般属性，二倍体酵母秸秆孢子化的频率升高，提高的可能性，秸秆的生理作用可能是传播孢子。
Stalk formation is a novel pattern of multicellular organization. Yeast cells which survive UV irradiation form colonies that grow vertically to form very long (0.5 to 3.0 cm) and thin (0.5 to 4 mm in diameter) multicellular structures. We describe the conditions required to obtain these stalk-like structures reproducibly in large numbers. Yeast mutants, mutated for control of cell polarity, developmental processes, UV response, and signal transduction cascades were tested and found capable of forming stalk-like structures. We suggest a model that explains the mechanism of stalk formation by mechanical environmental forces. We show that other microorganisms (Candida albicans, Schizosaccharomyces pombe, and Escherichia coli) also form stalks, suggesting that the ability to produce stalks may be a general property of microorganisms, Diploid yeast stalks sporulate at an elevated frequency, raising the possibility that the physiological role of stalks might be disseminating spores.