Fusion of high b-value diffusion-weighted and unenhanced T1-weighted images to diagnose invasive breast cancer: factors associated with false-negative results
Fusion of high b-value diffusion-weighted and unenhanced T1-weighted images to diagnose invasive breast cancer: factors associated with false-negative results
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DOI：
10.1007/s00330-020-07644-5
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发表时间：
2021-01-14
影响因子：
5.9
通讯作者：
Kim, Jin You
中科院分区：
文献类型：
--
作者：
Kim, Jin Joo;Kim, Jin You
目的：我们使用融合高 b 值扩散加权成像 (DWI) 和非增强 T1 加权图像 (T1WI)，通过非对比乳腺磁共振成像 (MRI) 寻找与诊断浸润性乳腺癌假阴性结果相关的因素。方法：2018 年至 2019 年间，连续 316 名患有浸润性乳腺癌的女性（平均年龄 54.6 岁）接受了术前乳腺 MRI，包括融合高 b 值扩散加权成像 (T1WI)。回顾性评估 b 值 DWI 和未增强 T1WI。融合 DWI 上最可疑的乳腺病变的恶性置信度由两名放射科医生使用 6 点 Likert 型量表得出。分析临床病理学和影像学特征。进行多变量回归分析以确定与诊断浸润性乳腺癌中假阴性 DWI 结果相关的因素。结果：在 316 例乳腺癌中，融合 DWI 产生 289 例 (91.5%) 真阳性结果和 27 例 (8.5%) 假阴性结果。多变量分析显示肿瘤尺寸小（
Objectives: We sought factors associated with false-negative results in the diagnosis of invasive breast cancer via non-contrast breast magnetic resonance imaging (MRI) using fused high b-value diffusion-weighted imaging (DWI) and unenhanced T1-weighted images (T1WI).Methods: Between 2018 and 2019, 316 consecutive women (mean age, 54.6 years) with invasive breast cancer who underwent preoperative breast MRI, including fused high b-value DWI and unenhanced T1WI, were retrospectively evaluated. Malignancy confidence ratings of the most suspicious breast lesions evident on fused DWI were derived by two radiologists using a 6-point Likert-type scale. Both clinicopathological and imaging features were analyzed. Multivariate regression analysis was performed to identify factors associated with false-negative DWI results in the diagnosis of invasive breast cancer.Results: Of the 316 breast cancers, fused DWI yielded 289 (91.5%) true-positive and 27 (8.5%) false-negative results. Multivariate analysis showed that small tumor size (