The influence of metabolites of digoxin and digitoxin on the86Rb-uptake assay

The influence of metabolites of digoxin and digitoxin on the86Rb-uptake assay
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地高辛和洋地黄毒苷代谢物对 86Rb 摄取测定的影响

DOI:
10.1007/bf00561801
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发表时间:
1973
影响因子:
2.9
通讯作者:
F. Belpaire
F. Belpaire
中科院分区:
医学3区
文献类型:
--
作者:
J. Kaufman;F. Belpaire

文献摘要

被引文献

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摘要本文研究了地高辛和地地黄毒素代谢产物对红细胞86rb摄取的影响。所有测试的代谢物都是86rb摄取的抑制剂,并可能影响通过该方法获得的地高辛和地地黄毒素血浆水平的结果。它们对红细胞的抑制活性与其心脏活动有关。
SummaryThe influence of metabolites of digoxin and digitoxin on86Rb-uptake by red blood cells was studied. All the metabolites tested were inhibitors of86Rb-uptake and could influence the results obtained by this assay method for plasma levels of digoxin and digitoxin. Their inhibitory activity on red cells was related to their cardioactivity.