Primary breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
Primary breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
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DOI：
10.1093/annonc/mdr371
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发表时间：
2011-09-01
影响因子：
50.5
通讯作者：
Cardoso, F.
中科院分区：
文献类型：
--
作者：
Aebi, S.;Davidson, T.;Cardoso, F.
2008年，欧洲（40个国家）经年龄调整后的乳腺癌年发病率估计为88.4/10万，死亡率为24.3/10万。由于乳房x光检查和人口老龄化，发病率正在增加；绝经后激素替代疗法、西式饮食、肥胖以及烟酒消费是导致乳腺癌发病率上升的原因。有一个陡峭的年龄梯度，大约四分之一的乳腺癌发生在50岁之前，小于5%发生在35岁之前。在大多数西方国家，由于治疗方法的改进和早期发现，死亡率近年来有所下降，特别是在较年轻的年龄组。然而，乳腺癌仍然是欧洲妇女癌症相关死亡的主要原因。
In 2008 the estimated age-adjusted annual incidence of breast cancer in Europe (40 countries) was 88.4/100 000 and the mortality 24.3/100000. The incidence is increasing due to mammographic screening and an aging population; postmenopausal hormone replacement therapy, Western-style diet, obesity and consumption of alcohol and tobacco contribute to the rising incidence of breast cancer. There is a steep age gradient, with about a quarter of breast cancers occurring before age 50, and< 5% before age 35. In most Western countries, the mortality rate has decreased in recent years, especially in younger age groups because of improved treatment and earlier detection. However, breast cancer is still the leading cause of cancer-related deaths in European women.