Outpatient Management of Severe COPD.
Outpatient Management of Severe COPD.
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DOI：
10.1056/nejmcp0912556
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发表时间：
2010-04-15
影响因子：
158.5
通讯作者：
Niewoehner, Dennis E.
中科院分区：
文献类型：
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作者：
Niewoehner, Dennis E.
一位67岁的男性，表现为进行性呼吸困难。他从15岁起就开始抽烟。日益恶化的呼吸困难迫使他退休当工人。他的体格检查是值得注意的遥远的呼吸音听诊，延长呼气相。肺量测定显示严重气流阻塞（第一秒用力呼气量[FEV 1]与用力肺活量的比值为0.43; FEV 1为预测值的34%）。这种情况应该如何处理？
A 67-year-old man presents with progressive dyspnea. He has smoked cigarettes since he was 15 years of age. Worsening breathlessness forced him to retire as a laborer. His physical examination is notable for distant breath sounds on auscultation, with a prolonged expiratory phase. Spirometry reveals severe airflow obstruction (ratio of forced expiratory volume in first second [FEV1] to forced vital capacity, 0.43; FEV1, 34% of the predicted value). How should this case be managed?