Fabrication of fritless chromatographic microchips packed with conventional reversed-phase silica particles.
Fabrication of fritless chromatographic microchips packed with conventional reversed-phase silica particles.
复制标题
制造填充有传统反相二氧化硅颗粒的无熔块色谱微芯片。
DOI:
10.1021/ac071106g
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发表时间:
2007
影响因子:
7.4
通讯作者:
Gomez,FrankA
中科院分区:
文献类型:
--
作者:
Gaspar,Attila;Piyasena,MenakeE;Gomez,FrankA
This paper describes the development and study of a disposable and inexpensive microfluidic chip, fabricated from poly(dimethylsiloxane) (PDMS) incorporating conventional chromatographic reversed-phase silica particles (C18) without the use of frits, permanent physical barriers, tapers, or restrictors. The packing of C18 modified silica particles into the microfluidic channels is made possible by the hydrophobic nature and excellent elasticity of PDMS. Keystone-, clamping-, and anchor-effects provide the stability and the compactness of the packing and attenuated wall-effects were observed.
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DOI:
10.1073/pnas.80.11.3269
发表时间:
1983
影响因子:
11.1
作者:
Faltynek,CR;Branca,AA;McCandless,S;Baglioni,C
通讯作者:
Baglioni,C
DOI:
--
发表时间:
1981
期刊:
影响因子:
--
作者:
R. Friedman
通讯作者:
R. Friedman
DOI:
10.1016/s0021-9258(18)34579-4
发表时间:
1982
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
K. Zoon;D. zur Nedden;H. Arnheiter
通讯作者:
H. Arnheiter
DOI:
--
发表时间:
1983
期刊:
Journal of Interferon Research
影响因子:
--
作者:
A. Branca;S. D'Alessandro;C. Baglioni
通讯作者:
C. Baglioni
DOI:
--
发表时间:
1982
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
Andersen,TT;ReichertJr,LE
通讯作者:
ReichertJr,LE