Carboxyhemoglobin concentration in fetal cord blood.
Carboxyhemoglobin concentration in fetal cord blood.
复制标题
胎儿脐带血中碳氧血红蛋白浓度。
作者：
R. Huch;A. Huch;P. Tuchschmid;W. Zijlstra;A. Zwart
致编辑
Bureau等人1报告称，吸烟母亲的新生儿脐带血中的碳氧血红蛋白（HbCO）浓度比母体静脉血中的相应值增加两倍以上。数据来自IL 282（Instrumentation Laboratory，列克星敦）一氧化碳血氧计，该仪器使用全血中HbO2、Hb、MetHb和HbCO的光谱多组分分析。
我们担心所提供的数据是由于HbCO测量的伪影，因为所用仪器不适合正确测量胎儿血液中的HbCO浓度。
To the Editor.—
Bureau et al1 reported that the concentration of carboxyhemoglobin (HbCO) is increased more than twofold in cord blood of newborns of smoking mothers as compared to corresponding values in maternal venous blood. Data were obtained from an IL 282 (Instrumentation Laboratory, Lexington) Co-oximeter, an instrument using spectroscopic multicomponent analysis of HbO2, Hb, MetHb, and HbCO in whole blood.
We are concerned that the data presented are due to an artifact of HbCO measurement as the instrument used is not suitable for the correct measurement of HbCO concentrations in fetal blood.