Randomized controlled trial of surface peroneal nerve stimulation for motor relearning in lower limb hemiparesis.

Randomized controlled trial of surface peroneal nerve stimulation for motor relearning in lower limb hemiparesis.
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DOI:
10.1016/j.apmr.2013.01.024
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发表时间:
2013-06
影响因子:
4.3
通讯作者:
Chae, John
Chae, John
中科院分区:
医学1区
文献类型:
--
作者:
Sheffler, Lynne R.;Taylor, Paul N.;Gunzler, Douglas D.;Buurke, Jaap H.;IJzerman, Maarten J.;Chae, John

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比较腓表面神经刺激器(PNS)与常规护理对慢性脑卒中幸存者下肢运动障碍、活动限制和生活质量的运动再学习效果。随机对照试验:学术医疗中心教学医院慢性脑卒中患者110例(脑卒中后12周),单侧偏瘫,背屈强度≤医学研究委员会量表4/5分,按运动损伤程度分层,随机分组,采用表面PNS装置或常规护理(踝关节足矫形器或无矫形器)干预进行行走训练。治疗12周,治疗后随访6个月。Fugl-Meyer (FM)评估(运动障碍)的下肢部分,在没有设备的情况下进行的改良Emory功能活动概况(mEFAP)(功能活动),以及卒中特定生活质量(SSQOL)量表。在FM、mEFAP、SSQOL原始评分上,治疗组主效应和时间交互效应均无显著性差异(p < 0.05)。三个原始评分的时间效应均显著(p<0.05)。然而,当比较从基线(T1)到治疗结束、(T2、12周)以及治疗结束后12周(T3)和24周(T4)的平均变化评分时,只有mEFAP和SSQOL评分存在显著差异。mEFAP和SSQOL的平均得分在T1和T2之间发生变化,之后相对稳定。在PNS组和常规护理组中,没有证据表明运动再学习对下肢运动损伤有影响。然而,在治疗期间,PNS组和常规护理组均表现出功能活动能力和生活质量的显著改善,并在6个月的随访中保持不变。
To compare the motor relearning effect of a surface peroneal nerve stimulator (PNS) versus usual care on lower limb motor impairment, activity limitation, and quality of life among chronic stroke survivors. Single-blinded randomized controlled trial Teaching hospital of academic medical center 110 chronic stroke survivors (> 12-wks post-stroke) with unilateral hemiparesis and dorsiflexion strength of ≤ 4/5 on the Medical Research Council scale Subjects were stratified by motor impairment level and then randomized to ambulation training with either a surface PNS device or usual care (ankle foot orthosis or no device) intervention. Subjects were treated for 12-wks and followed for 6-months post-treatment. Lower limb portion of the Fugl-Meyer (FM) Assessment (motor impairment), the Modified Emory Functional Ambulation Profile (mEFAP) performed without a device (functional ambulation), and the Stroke Specific Quality of Life (SSQOL) scale. There was no significant treatment group main effect or treatment group by time interaction effect on FM, mEFAP, or SSQOL raw scores (p>0.05). The time effect was significant for the three raw scores (p<0.05). However, when comparing average change scores from baseline (T1) to end of treatment, (T2, 12-wks), and at 12-wks (T3) and 24-wks (T4) after end of treatment, significant differences were noted only for the mEFAP and SSQOL scores. The change in the average scores for both mEFAP and SSQOL occurred between T1 and T2, followed by relative stability thereafter. There was no evidence of a motor relearning effect on lower limb motor impairment in either the PNS or usual care groups. However, both PNS and usual care groups demonstrated significant improvements in functional mobility and quality of life during the treatment period, which were maintained at 6-months follow-up.
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