G-Protein-coupled receptors: Lipidated peptides: a therapeutic tool kit

G-Protein-coupled receptors: Lipidated peptides: a therapeutic tool kit
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DOI:
10.1038/nrd929
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发表时间:
2002
影响因子:
120.1
通讯作者:
Melanie I. Brazil
Melanie I. Brazil
中科院分区:
医学1区
文献类型:
--
作者:
Melanie I. Brazil

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引用由L. Covic及其同事在2002年10月出版的《自然医学》杂志上发表的“pepducin诱导的凝血酶受体信号和系统性血小板激活的干预”研究。蛋白酶激活受体1和蛋白酶激活受体4可溶性肽配体的肽肽抑制作用g蛋白偶联受体(GPCR)的细胞穿透性、膜栓性肽激活GPCR信号中断的影响。
Cites the study'Pepducin-induced intervention of thrombin receptor signalling and systematic platelet activation,'conducted by L. Covic and colleagues, published in the October 2002 issue of'Nature Medicine.'Inhibition of soluble peptide ligands of protease-activated receptor 1 and protease-activated receptor 4 by their respective pepducins; Activation of G-protein-coupled receptors (GPCR) by cell penetrating, membrane-tethered peptides; Effects of the disruption of GPCR signalling.