Rotavirus genotypes co-circulating in Europe between 2006 and 2009 as determined by EuroRotaNet, a pan-European collaborative strain surveillance network
Rotavirus genotypes co-circulating in Europe between 2006 and 2009 as determined by EuroRotaNet, a pan-European collaborative strain surveillance network
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DOI：
10.1017/s0950268810001810
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发表时间：
2011-06-01
影响因子：
4.2
通讯作者：
Gray, J.
中科院分区：
文献类型：
--
作者：
Iturriza-Gomara, M.;Dallman, T.;Gray, J.
欧洲轮状病毒网络是一个实验室网络，它的建立是为了确定2006/2007年三个或三个以上轮状病毒季节欧洲共同传播的轮状病毒株的多样性，目前包括16个国家。这份报告强调了自2006/2007年以来的三年监测期间在欧洲人群中共同传播的轮状病毒毒株的巨大多样性，并指出了这些毒株的可能来源，包括基因重组和物种间传播。此外，该网络识别发病率为1%的流行菌株的能力使得自研究开始以来就识别了可能出现的新菌株，如G8和G12；对最近数据的分析表明它们的发病率有所增加。至少在两个参与国实行普遍轮状病毒疫苗接种，以及其他一些国家的部分疫苗覆盖率，可能会提供关于欧洲引进疫苗和可能的毒株替换所推动的多样性的数据。
EuroRotaNet, a laboratory network, was established in order to determine the diversity of co-circulating rotavirus strains in Europe over three or more rotavirus seasons from 2006/2007 and currently includes 16 countries. This report highlights the tremendous diversity of rotavirus strains co-circulating in the European population during three years of surveillance since 2006/2007 and points to the possible origins of these strains including genetic reassortment and interspecies transmission. Furthermore, the ability of the network to identify strains circulating with an incidence of >= 1% allowed the identification of possible emerging strains such as G8 and G12 since the beginning of the study; analysis of recent data indicates their increased incidence. The introduction of universal rotavirus vaccination in at least two of the participating countries, and partial vaccine coverage in some others may provide data on diversity driven by vaccine introduction and possible strain replacement in Europe.