Current trends in implantable left ventricular assist devices.
Current trends in implantable left ventricular assist devices.
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DOI：
10.4061/2011/290561
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发表时间：
2011
影响因子：
2.1
通讯作者：
Mohr FW
中科院分区：
文献类型：
--
作者：
Garbade J;Bittner HB;Barten MJ;Mohr FW
合适的供体器官的短缺和等待心脏移植的患者的不断扩大导致人们对替代策略的兴趣日益增加，特别是在机械循环支持方面。左心室辅助装置（LVAD）的改善结果以及更高的适用性和耐用性增强了终末期心力衰竭患者的治疗选择。此外，新型胰岛素泵的结局已发展为此类患者的目的地治疗。目前，使用非脉动连续流泵的结果记录了在具有里程碑意义的充血性心力衰竭治疗机械辅助随机评价试验（REMATCH）之后实现的目标治疗后结局的演变，以及脉动设计的第二代LVAD的结局。本文综述了目前可用的LVAD类型、临床应用和结局，并重点介绍了患者选择过程。
The shortage of appropriate donor organs and the expanding pool of patients waiting for heart transplantation have led to growing interest in alternative strategies, particularly in mechanical circulatory support. Improved results and the increased applicability and durability with left ventricular assist devices (LVADs) have enhanced this treatment option available for end-stage heart failure patients. Moreover, outcome with newer pumps have evolved to destination therapy for such patients. Currently, results using nonpulsatile continuous flow pumps document the evolution in outcomes following destination therapy achieved subsequent to the landmark Randomized Evaluation of Mechanical Assistance for the Treatment of Congestive Heart Failure Trial (REMATCH), as well as the outcome of pulsatile designed second-generation LVADs. This review describes the currently available types of LVADs, their clinical use and outcomes, and focuses on the patient selection process.