Early Detection of Physical Activity for People With Type 1 Diabetes Mellitus.
Early Detection of Physical Activity for People With Type 1 Diabetes Mellitus.
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DOI：
10.1177/1932296815592409
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发表时间：
2015-06-30
影响因子：
5
通讯作者：
Dassau, Eyal
中科院分区：
文献类型：
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作者：
Dasanayake, Isuru S;Bevier, Wendy C;Dassau, Eyal
背景：在1型糖尿病(T1 DM)患者中及早发现运动可能有助于改变治疗方法以预防低血糖。目前，在这一人群中检测运动开始和结束的自动化方法的经验有限。我们试图开发一种新的方法，在血糖(BG)发生显著变化之前，快速可靠地检测这些人运动的开始和结束。方法：以16名成年T1 DM患者为研究对象，使用日记、加速度计、心率监测仪和连续血糖监测仪进行为期2天的研究。这些数据被用来开发基于主成分分析的运动检测方法。受试者还分别以30%和50%的预测心率储备(HRR)进行了60分钟和30分钟的锻炼。结果：轻度30%HRR和中度50%HRR分别在6±3和5±2分钟内开始运动，而运动结束分别在3±8分钟和6±5分钟内完成。两次运动开始至检测时间的血糖变化分别为1±6和-1±3 mg/dL，运动结束至检测时间的血糖变化分别为6±4和-17±13 mg/dL。假阳性率和假阴性率分别为4±2%和21±22%。结论：该运动检测方法能在约5min内识别运动的开始和结束，平均血糖变化仅为-6 mg/dL。
BACKGROUND: Early detection of exercise in individuals with type 1 diabetes mellitus (T1DM) may allow changes in therapy to prevent hypoglycemia. Currently there is limited experience with automated methods that detect the onset and end of exercise in this population. We sought to develop a novel method to quickly and reliably detect the onset and end of exercise in these individuals before significant changes in blood glucose (BG) occur.METHODS: Sixteen adults with T1DM were studied as outpatients using a diary, accelerometer, heart rate monitor, and continuous glucose monitor for 2 days. These data were used to develop a principal component analysis based exercise detection method. Subjects also performed 60 and 30 minute exercise sessions at 30% and 50% predicted heart rate reserve (HRR), respectively. The detection method was applied to the exercise sessions to determine how quickly the detection of start and end of exercise occurred relative to change in BG.RESULTS: Mild 30% HRR and moderate 50% HRR exercise onset was identified in 6 ± 3 and 5 ± 2 (mean ± SD) minutes, while completion was detected in 3 ± 8 and 6 ± 5 minutes, respectively. BG change from start of exercise to detection time was 1 ± 6 and -1 ± 3 mg/dL, and, from the end of exercise to detection time was 6 ± 4 and -17 ± 13 mg/dL, respectively, for the 2 exercise sessions. False positive and negative ratios were 4 ± 2% and 21 ± 22%.CONCLUSIONS: The novel method for exercise detection identified the onset and end of exercise in approximately 5 minutes, with an average BG change of only -6 mg/dL.