Left ventricular function in chronic obstructive lung disease.
Left ventricular function in chronic obstructive lung disease.
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慢性阻塞性肺疾病的左心室功能。
DOI：
10.1056/nejm197108122850701
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发表时间：
1971
期刊：
影响因子：
--
通讯作者：
C. Castillo
中科院分区：
文献类型：
--
作者：
G. L. Baum;A. Schwartz;R. Llamas;C. Castillo
对15例慢性阻塞性肺疾病患者行双室心导管检查，发现7例左室舒张末压升高，14例左心功能曲线异常。左心室造影分析显示10例中9例室壁增厚或舒张期内径增大(或两者兼有)，8例中3例室壁功能减退。功能损害的程度不受右心衰的存在或不存在的影响。在电影血管造影术研究的10名受试者中，只有两人发现明显的冠状动脉狭窄。研究中的大多数患者都存在左心功能不全。其发病机制尚不清楚。
Abstract In 15 patients with chronic obstructive lung disease, biventricular cardiac catheterization showed that left ventricular end-diastolic pressure was elevated in seven, and abnormal left ventricular function curves were found in 14. Analysis of left ventriculography revealed increased wall thickness or diastolic chamber size (or both) in nine of 10 observations and impaired ventricular performance in three of eight. The degree of functional impairment was not influenced by the presence or absence of right-sided heart failure. Appreciable coronary narrowing was found in only two of 10 subjects studied by cineangiography. Left ventricular dysfunction was present in most of the patients studied. The pathogenesis of the dysfunction is not clear.