EFFECT OF TRAINING ON ENZYME-ACTIVITY AND FIBER COMPOSITION OF HUMAN SKELETAL-MUSCLE
EFFECT OF TRAINING ON ENZYME-ACTIVITY AND FIBER COMPOSITION OF HUMAN SKELETAL-MUSCLE
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DOI：
10.1152/jappl.1973.34.1.107
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发表时间：
1973-01-01
影响因子：
3.3
通讯作者：
SHEPHERD, RE
中科院分区：
文献类型：
--
作者：
GOLLNICK, PD;ARMSTRON.RB;SHEPHERD, RE
材料和方法研究了6名健康男性受试者（身体特征见表1）。所有人都积极参加娱乐运动，但在本研究之前没有人参加耐力训练至少2年。在训练前，测定最大耗氧量（VOW，），并采用针吸活检技术从股肌外侧部分的两个不同部位采集肌肉样本（4）。受试者进行为期5个月的训练，每天踏车1小时，每周4天，负荷量为最大有氧功率的75%。最初，受试者不能耐受整个小时的这种负荷，并且在运动回合的一部分期间，它被降低到约65%的VO，111 X。大约2周后，所有受试者都能完成1小时的基本训练负荷，此后，每个受试者都试图将工作负荷增加到1小时内所能承受的最大负荷。在训练计划100的中途，重复111 AX测试以确保所有受试者仍在规定的负荷下工作。在培训计划结束时，大多数受试者以其VO，max的85-90%工作1小时。
MATERIALS AND METHODSSix healthy male subjects were studied (see Table 1 for physical characteristics). All were active in recreationa sports but none had engaged in endurance training for at least 2 years prior to this study. Before training maximal oxygen consumption(VOW,,,) was determined and muscle samples were taken from two different sites in the lateral portion of the vastus muscle with the needle biopsy technique (4).The subjects proceeded to train for 5 months by pedaling a cycle ergometer 1 hr/day 4 days a week at a load requiring 75% of their maximal aerobic power. Initially the subjects could not tolerate this load for the full hour and it was reduced to about 65% of VO, lllitX during a portion of the exercise bout. After about 2 weeks all subjects were able to complete the basic training load for 1 hr. Thereafter each subject attempted to increase the work load to the maximum that could be tolerated for the l-hr period. Midway through the training program 00, lllaX tests were repeated to ensure that all subjects were still working at the prescribed load. At the end of the training program most of the subjects were working for 1 hr at 85-90% of their VO, max.