Acute Exercise Influences Reward Processing in Highly Trained and Untrained Men
Acute Exercise Influences Reward Processing in Highly Trained and Untrained Men
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DOI：
10.1249/mss.0b013e318275306f
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发表时间：
2013-03-01
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影响因子：
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通讯作者：
Stroehle, Andreas
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文献类型：
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作者：
Bothe, Nina;Zschucke, Elisabeth;Stroehle, Andreas
BOTHE，N.，E.茨丘克迪梅奥，A.海因茨WUSTENBERG，A.斯特罗。急性运动影响高度训练和未经训练的男性的奖励处理。医学科学体育锻炼：第45卷，第3期，第100页。583-591，2013。简介：身体活动激活大脑区域和代表奖励系统的传输系统（即，腹侧纹状体[VS]和多巴胺）。迄今为止，训练状态和急性运动对奖励处理的影响尚未在人类中进行系统研究。为了解决这个问题，我们研究了训练有素（HT）的身体不活跃（PIA）的人与金钱激励延迟（MID）的范例。研究方法：我们使用功能性磁共振成像（fMRI）来研究急性运动后金钱激励处理的神经相关性。HT和PIA受试者被随机分为两组。一组受试者在跑步机（T）上以其最大摄氧量的60%-70%（（V）超过dot 0（2 max））跑30分钟，而另一组受试者进行安慰剂运动（P）。运动后约1小时，进行MID任务。在运动干预前后，使用积极和消极情绪量表评估情绪。结果：心理评估显示，运动显着增加HT和PIA男性的情绪。在MID任务的增益预期和增益反馈期间，安慰剂组的VS比跑步机组显著更强激活。没有发现训练状态的影响，训练状态和剧烈运动之间也没有相互作用。结论：剧烈运动会降低人类对金钱奖励的敏感性。这一发现进行了讨论，关于紧张和相位多巴胺在VS之间的相互作用。
BOTHE, N., E. ZSCHUCKE, F. DIMEO, A. HEINZ, T. WUSTENBERG, and A. STROHLE. Acute Exercise Influences Reward Processing in Highly Trained and Untrained Men. Med. Sci. Sports Exerc., Vol. 45, No. 3, pp. 583-591, 2013. Introduction: Physical activity activates brain regions and transmitter systems that represent the reward system (i.e., the ventral striatum [VS] and dopamine). To date, the effect of training status and acute exercise on reward processing has not been investigated systematically in humans. To address this issue, we examined highly trained (HT) physically inactive (PIA) men with a monetary incentive delay (MID) paradigm. Methods: We used functional magnetic resonance imaging (fMRI) to investigate the neural correlates of monetary incentive processing after acute exercise. HT and PIA subjects were randomized into two groups. Subjects in one group ran on a treadmill (T) for 30 min at 60%-70% of their maximal oxygen uptake ((V) over dotO(2max)), whereas subjects in the other group performed placebo exercise (P). Approximately 1 h after exercise, the MID task was conducted. Mood was assessed using the Positive and Negative Affect Schedule before and after the exercise intervention. Results: The psychological assessment showed that exercise significantly increased mood in HT and PIA men. During gain anticipation and gain feedback of the MID task, the VS was significantly stronger activated in the placebo group than in the treadmill group. No effect of training status and no interactions between training status and acute exercise were found. Conclusions: Acute exercise diminishes sensitivity to monetary rewards in humans. This finding is discussed concerning interactions between tonic and phasic dopamine in the VS.