Coordinated and Fine-Scale Control of Homoeologous Gene Expression in Allotetraploid Cotton
Coordinated and Fine-Scale Control of Homoeologous Gene Expression in Allotetraploid Cotton
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DOI：
10.1093/jhered/esp003
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发表时间：
2009-07-01
影响因子：
3.1
通讯作者：
Wendel, Jonathan F.
中科院分区：
文献类型：
--
作者：
Flagel, Lex E.;Chen, Liping;Wendel, Jonathan F.
在多倍体植物物种中，已证明同源基因（通过多倍体复制的基因）通常表现出动态表达模式。为了确定染色体位置是否在建立这些表达模式中发挥作用，我们分析了棉花基因组中两个位置的连锁基因之间同源表达的相对水平。来自含有醇脱氢酶 A 基因的区域的基因在多个组织中显示出协调表达，而来自含有纤维素合酶 A 的区域的基因则不然。这些结果表明，同源基因表达的变化可能受到某些基因组区域中连锁的限制，而在其他区域，同源基因表达在很大程度上与物理邻近性脱钩。此外，这些结果表明大规模和小规模的调控机制都可以控制同源基因的表达模式。
Within polyploid plant species, it has been demonstrated that homoeologous genes (genes duplicated by polyploidy) often display dynamic expression patterns. To determine if chromosomal location plays a role in establishing these expression patterns, we analyzed the relative levels of homoeolog expression among linked genes from 2 locations in the cotton genome. Genes from the region containing the alcohol dehydrogenase A gene show coordinated expression across several tissues, whereas genes from the region containing cellulose synthase A do not. These results indicate that changes in homoeolog expression may be constrained by linkage in some genomic regions, whereas in other regions, homoeolog expression is largely decoupled from physical proximity. Furthermore, these results suggest that both large- and small-scale regulatory mechanisms may control homoeolog expression patterns.