Stone Composition as a Function of Age and Sex

Stone Composition as a Function of Age and Sex
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DOI:
10.2215/cjn.05660614
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发表时间:
2014-12-01
影响因子:
9.8
通讯作者:
Moyer, Thomas P.
Moyer, Thomas P.
中科院分区:
医学1区
文献类型:
--
作者:
Lieske, John C.;Rule, Andrew D.;Moyer, Thomas P.

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背景和目的肾结石是异质性的,但往往聚集在一起。设计、设置、参与者和测量研究了2010年期间患者提交给马约诊所金属实验室进行分析的第一块结石(n= 43,545)。结果草酸钙结石(67%)最常见,其次为羟基磷灰石(16%)、尿酸(8%)、鸟粪石(3%)、透钙磷石(0.9%)和胱氨酸(0.35%)。男性比女性占更多的石头提交(58%)。然而,在10-19岁(63%)和20-29岁(62%)之间,女性提交的钻石数量多于男性。女性以羟基磷灰石(65%)和鸟粪石(65%)结石为主,而男性以草酸钙(64%)和尿酸(72%)结石为主(P
Background and objectives Kidney stones are heterogeneous but often grouped together. The potential effects Of patient demographics and calendar month (season) on stone composition are not widely appreciated.Design, setting, participants, & measurements The first stone submitted by patients for analysis to the Mayo Clinic Metals Laboratory during 2010 was studied (n=43,545). Stones were classified in the following order: any struvite, any cystine, any uric acid, any brushite, majority (>= 50%) calcium oxalate, or majority (>= 50%) hydroxyapatite.Results Calcium oxalate (67%) was the most common followed by hydroxyapatite (16%), uric acid (8%), struvite (3%), brushite (0.9%), and cystine (0.35%). Men accounted for more stone submissions (58%) than women. However, women submitted more stones than men between the ages of 10-19 (63%) and 20-29 (62%) years. Women submitted the majority of hydroxyapatite (65%) and struvite (65%) stones, whereas men submitted the majority of calcium oxalate (64%) and uric acid (72%) stones (P