Functional anatomy of musical processing in listeners with absolute pitch and relative pitch.
Functional anatomy of musical processing in listeners with absolute pitch and relative pitch.
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DOI：
10.1073/pnas.95.6.3172
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发表时间：
1998-03
影响因子：
11.1
通讯作者：
R. Zatorre;D. Perry;C. Beckett;C. Westbury;Alan C. Evans
中科院分区：
文献类型：
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作者：
R. Zatorre;D. Perry;C. Beckett;C. Westbury;Alan C. Evans
我们使用结构和功能脑成像技术来研究绝对音高(AP)的神经基础，这是一些音乐家存在的一种特殊技能。通过使用正电子发射断层扫描，我们测量了音乐音调呈现给AP的人和没有AP的音乐家的脑血流量。正如预期的那样，在两组人中，听音乐导致大脑皮质区域血流增加的模式相似。AP组还表现出左侧后背外侧额叶皮质的激活，该区域被认为与学习条件联想有关。然而，当非AP受试者对音程(如小调或大调)进行相对音调判断时，也观察到类似的左背外侧额叶活动模式。相反，在间隔判断任务中，控制组观察到右额叶下部皮质的活动，而AP受试者没有，这表明AP持有者在这项任务中不需要访问工作记忆机制。核磁共振测量皮质体积显示AP组的左侧颞叶平面较大，这与音高命名任务中的表现相关。我们的发现表明，AP可能与大脑活动的独特模式无关，而可能依赖于参与提取和操纵言语-音调联系的专门网络的招募。
We used both structural and functional brain imaging techniques to investigate the neural basis of absolute pitch (AP), a specialized skill present in some musicians. By using positron emission tomography, we measured cerebral blood flow during the presentation of musical tones to AP possessors and to control musicians without AP. Listening to musical tones resulted in similar patterns of increased cerebral blood flow in auditory cortical areas in both groups, as expected. The AP group also demonstrated activation of the left posterior dorsolateral frontal cortex, an area thought to be related to learning conditional associations. However, a similar pattern of left dorsolateral frontal activity was also observed in non-AP subjects when they made relative pitch judgments of intervals, such as minor or major. Conversely, activity within the right inferior frontal cortex was observed in control but not in AP subjects during the interval-judgment task, suggesting that AP possessors need not access working memory mechanisms in this task. MRI measures of cortical volume indicated a larger left planum temporale in the AP group, which correlated with performance on an pitch-naming task. Our findings suggest that AP may not be associated with a unique pattern of cerebral activity but rather may depend on the recruitment of a specialized network involved in the retrieval and manipulation of verbal-tonal associations.