Screening for esophageal squamous cell carcinoma: recent advances.
Screening for esophageal squamous cell carcinoma: recent advances.
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DOI：
10.1016/j.gie.2018.04.2352
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发表时间：
2018-09
影响因子：
7.7
通讯作者：
Iyer PG
中科院分区：
文献类型：
--
作者：
Codipilly DC;Qin Y;Dawsey SM;Kisiel J;Topazian M;Ahlquist D;Iyer PG
食管鳞状细胞癌（ESCC）是世界范围内最常见的食管癌类型，由于诊断阶段较晚，死亡率很高。虽然在从里海延伸到中国北部的亚洲食管癌带和非洲部分地区最为常见，但世界其他地方也存在高风险人群。ESCC筛查已在少数地理区域和高危人群中实施，取得了不同程度的成功。食管鳞状发育不良被认为是ESCC的前兆病变。内镜筛查ESCC/食管鳞状发育不良是昂贵的，在许多高风险地区没有足够的可用性。基于生物标志物的疾病检测增强了非内镜筛查的最新进展，提高了食管鳞状异常增生和早期ESCC筛查的准确性和可用性的前景。开发一种具有成本效益、准确和耐受性良好的筛查试验，如果在流行地区和高危人群中应用，就有可能在世界范围内降低这一致命疾病的死亡率。在这篇综述中，我们总结了内镜和非内镜筛查方式的最新进展。
Esophageal squamous cell carcinoma (ESCC) is the most common type of esophageal cancer worldwide, with a high mortality due to advanced stage at diagnosis. Although most common in an area known as the Asian Esophageal Cancer Belt, which extends from the Caspian Sea to northern China, and in parts of Africa, high-risk populations also exist elsewhere in the world. Screening for ESCC has been practiced in a few geographic areas and high-risk populations, with varying levels of success. Esophageal squamous dysplasia is recognized as the precursor lesion for ESCC. Endoscopic screening for ESCC/esophageal squamous dysplasia is expensive and not sufficiently available in many high-risk regions. Recent advances in non-endoscopic screening enhanced by biomarker-based disease detection have raised the prospect of improved accuracy and availability of screening for esophageal squamous dysplasia and early stage ESCC. Development of a cost-effective, accurate, and well-tolerated screening test, if applied in endemic areas and high-risk populations, has the potential to reduce mortality from this deadly disease worldwide. In this review, we summarize recent developments in endoscopic and non-endoscopic screening modalities.
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DOI：
10.4321/s1130-01082013000200004
发表时间：
2013-02-01
期刊：
Revista Española de Enfermedades Digestivas
影响因子：
--
作者：
Carvalho, Rita;Areia, Miguel;Cadime, Ana Teresa
通讯作者：
Cadime, Ana Teresa
影响因子：
3.8
作者：
Morita FH;Bernardo WM;Ide E;Rocha RS;Aquino JC;Minata MK;Yamazaki K;Marques SB;Sakai P;de Moura EG
通讯作者：
de Moura EG
影响因子：
3.7
作者：
Aghcheli K;Marjani HA;Nasrollahzadeh D;Islami F;Shakeri R;Sotoudeh M;Abedi-Ardekani B;Ghavamnasiri MR;Razaei E;Khalilipour E;Mohtashami S;Makhdoomi Y;Rajabzadeh R;Merat S;Sotoudehmanesh R;Semnani S;Malekzadeh R
通讯作者：
Malekzadeh R
影响因子：
2.9
作者：
Arantes, Vitor;Albuquerque, Walton;Vaz Coelho, Luiz Gonzaga
通讯作者：
Vaz Coelho, Luiz Gonzaga
影响因子：
3.2
作者：
Huang, Yueng-Hsiang;Lee, Jin;Zohar, Dov
通讯作者：
Zohar, Dov