Commentary: Strong or Weak Phase Resetting by Light Pulses in Humans?
Commentary: Strong or Weak Phase Resetting by Light Pulses in Humans?
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评论：人类光脉冲的强相位重置还是弱相位重置？
DOI：
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发表时间：
1993
影响因子：
3.5
通讯作者：
P. Lakin
中科院分区：
文献类型：
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作者：
P. Lakin
最近在人类中通过光进行明显的 0 型重置的证明（Czeisler 等人，1989）引发了关于数据解释的令人惊讶的争议（Beersma 和 Daan，本期）。令人惊讶的是，数据似乎表明人类昼夜节律振荡器的行为正如成功描述其他几个物种的振荡器的理论所预测的那样。人们本以为这一论证会立即被接受，因为它与我们对其他生物体昼夜节律振荡器的了解是一致的。那么，为什么人们会抵制将人类纳入昼夜节律大家庭呢？困难源于 Czeisler 等人使用的非常规多脉冲协议。 （1989）。我想说的是，如果我们对人类数据应用相同的标准
The recent demonstration of apparent type 0 resetting by light in humans (Czeisler et al., 1989) has provoked a surprising controversy over the interpretation of the data (Beersma and Daan, this issue). It is surprising because the data seem to indicate that the human circadian oscillator behaves as predicted by theories that successfully describe the oscillators in several other species. One would have expected this demonstration to be immediately acceptable, on the grounds that it is consistent with what we know about circadian oscillators in other organisms. Why, then, this resistance to bringing humans into the circadian family? The difficulty arises from the unconventional multiple-pulse protocol used by Czeisler et al. (1989). I would like to argue that if we apply the same criteria to the human data that we