Advances in adult asthma diagnosis and treatment and HEDQ in 2010

Advances in adult asthma diagnosis and treatment and HEDQ in 2010
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DOI:
10.1016/j.jaci.2010.11.017
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发表时间:
2011-01-01
影响因子:
14.2
通讯作者:
Apter, Andrea J.
Apter, Andrea J.
中科院分区:
医学1区
文献类型:
--
作者:
Apter, Andrea J.

文献摘要

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本摘要回顾了过去一年发表的关于哮喘的研究,并通过医疗保健提供和质量的棱镜。特别注意的是管理,治疗和环境暴露的作用及其与遗传学的相互作用。讨论围绕转化研究的3个阶段进行:从实验室到人类受试者的首次研究,然后是在明确定义的患者人群中进行更大规模的疗效研究,最后是通过在现实世界中进行有效性研究而付诸实践。(J Allergy Clin Immunol 2011; 127:116 - 22.)
This summary reviews research published over the past year on asthma and through the prism of health care delivery and quality. Special attention is given to management, therapeutics, and the role of environmental exposures and their interactions with genetics. The discussion is framed around the 3 stages of translational research: from bench to first studies in human subjects, then to larger efficacy studies in well-defined patient populations, and finally into practice through effectiveness research in real-world settings. (J Allergy Clin Immunol 2011;127:116-22.)