Surveillance of Wastewater for Early Epidemic Prediction (SWEEP): Environmental and health security perspectives in the post COVID-19 Anthropocene.
Surveillance of Wastewater for Early Epidemic Prediction (SWEEP): Environmental and health security perspectives in the post COVID-19 Anthropocene.
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DOI：
10.1016/j.envres.2021.110831
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发表时间：
2021-04
影响因子：
8.3
通讯作者：
Kumar M
中科院分区：
文献类型：
--
作者：
Tiwari SB;Gahlot P;Tyagi VK;Zhang L;Zhou Y;Kazmi AA;Kumar M
本文总结了新冠肺炎污水流行病学研究的主要成果，提出了实施污水流行病学的概念框架--“污水监测及早流行预测”。SWEEP框架可能不会解决与WBE相关的几个实际问题，同时建议对该方法进行改进，以获得更好的结果和效率，以拯救全球各地的宝贵生命。据观察，目前的大流行提供了一个机会，可以将其纳入常规的城市水管理，把人类放在未来阻止这种大流行的最前列，或者至少做好与之作斗争的准备。在全球合作下，可以微调SWEEP以满足不同的需求，使现在和未来的几代人对未来的病毒爆发具有弹性。最近为检查废水中是否存在SARS-CoV-2而进行的WBE研究显示，未经处理的污水样本对基于聚合酶链式反应的检测呈阳性，而处理后的样本显示没有病毒滴度。此外，封锁对减少污水中的病毒载量产生了积极影响。对于预测大流行的阶段，所提出的SCEEP方案比个人证言具有优势。
The present work summarizes the major research findings related to wastewater-based epidemiology (WBE) study of COVID-19 and puts forward a conceptual framework, termed as “Surveillance of Wastewater for Early Epidemic Prediction (SWEEP)” for implementation of WBE. SWEEP framework is likely to tackle few practical issues related to WBE and simultaneously proposes refinements to the approach for better outcome and efficiency to save precious lives around the globe. It is observed that the present pandemic offers an opportunity for SWEEP to get included in routine urban water management to put the humankind at front to stop such pandemic in future or at least be prepared to fight against it. With global collaboration, SWEEP can be fine-tuned to meet diverse needs, making the present and future generations resilient to future viral outbreaks. Recent WBE studies conducted to check for the presence of SARS-CoV-2 in wastewater revealed that raw sewage samples tested positive to PCR-based assays while the treated samples showed absence of viral titers. Moreover, the lockdown had a positive impact on decreasing the viral loading in sewage. The proposed SWEEP protocol has an advantage over testifying individuals for predicting the stage of pandemic.