SYNTAX COMPREHENSION DEFICITS IN PARKINSONS-DISEASE
SYNTAX COMPREHENSION DEFICITS IN PARKINSONS-DISEASE
复制标题
DOI：
10.1097/00005053-199006000-00003
复制
发表时间：
1990-06-01
影响因子：
1.9
通讯作者：
FELDMAN, LS
中科院分区：
文献类型：
--
作者：
LIEBERMAN, P;FRIEDMAN, J;FELDMAN, LS
使用罗德岛语言结构测试对 39 名轻度至中度帕金森病 (PD) 患者对 100 个不同英语口语句子的理解进行了研究。其中 8 名 PD 患者患有轻度痴呆，其余 31 名患者没有表现出认知缺陷。八名轻度痴呆患者中的七名对于具有中等复杂语法的句子具有较高的理解错误率。其他 31 名非痴呆患者中有 28 名的错误率较低，与正常对照受试者相似。痴呆患者和非痴呆患者的错误率之间存在显着差异（p < .02，双尾 t 检验）。这些数据反对当前一些将语言与其他认知行为分开的“模块化”理论。 PD对刺激额叶皮层的中脑区域的破坏可能是造成认知和句法理解缺陷的原因。
The comprehension of 100 different spoken English sentences was studied in 39 patients with mild to moderate Parkinson''s disease (PD) using the Rhode Island Test of Language Structure. Eight of the PD patients were mildly demented, and the remaining 31 showed no cognitive deficits. Seven of the eight mildly demented patients had high comprehension error rates for sentences that had moderately complex syntax. The error rates of 28 of the 31 other, nondemented patients were low, similar to those of normal control subjects. The difference between the error rates of the demented and nondemented patients was significant (p < .02, two-tailed t-test). The data argue against some current "modular" theories that segregate linguistic from other cognitive behavior. The destruction by PD of the midbrain regions that stimulate the frontal cortex may be responsible for both cognitive and sytactic comprehension deficits.