Oxonium ylide rearrangement of enzymatically desymmetrized glutarates.
Oxonium ylide rearrangement of enzymatically desymmetrized glutarates.
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DOI：
10.1021/ol402887z
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发表时间：
2013-11
期刊：
影响因子：
5.2
通讯作者：
Benedikt Skrobo;J. Deska
中科院分区：
文献类型：
--
作者：
Benedikt Skrobo;J. Deska
The combination of an enzyme-mediated enantioselective desymmetrization of readily available 3-benzyloxyglutarates and subsequent rhodium-catalyzed oxonium ylide rearrangement of their corresponding in situ derived diazo ketones offers a very concise and highly stereoselective access to functionalized tetrahydrofuranone building blocks.
