Inability of diffusion to account for placental glucose transfer in the sheep and consideration of the kinetics of a possible carrier transfer
Inability of diffusion to account for placental glucose transfer in the sheep and consideration of the kinetics of a possible carrier transfer
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扩散无法解释绵羊胎盘葡萄糖转移并考虑可能的载体转移动力学
DOI：
10.1113/jphysiol.1952.sp004770
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发表时间：
1952
期刊：
影响因子：
--
通讯作者：
W. F. Widdas
中科院分区：
文献类型：
--
作者：
W. F. Widdas
1型。母羊的高血糖。给怀孕的母羊注射2 g/kg体重的葡萄糖会引起母体和胎儿糖水平的特征性变化，如图1所示。该图中的点代表Huggett等人进行的四次此类实验的平均值（数据由私人通信提供）。在静脉注射期间，母亲的血糖水平可能上升到700 - 800毫克/100毫升，但在随后的3小时内下降。胎儿葡萄糖在前半小时急剧上升至200 mg/100 ml左右，然后开始下降，而胎儿果糖则呈现稳定且持续时间较长的上升趋势。
Type 1. Hyperglycaemia in the ewe. Injection of glucose into pregnant ewes in doses of 2 g/kg body wt. causes characteristic changes in the maternal and foetal sugar levels which are illustrated in Fig. 1. The points in this graph represent the mean of four such experiments by Huggett et al.(Data supplied by private communication.)During the intravenous injection the maternal blood glucose level probably rises to between 700 and 800 mg/100 ml. but falls off over the subsequent 3 hr. The foetal glucose rises steeply during the first half-hour to about 200 mg/100 ml. and then starts to decline, while the foetal fructose shows a steady and more prolonged rise.