IQ and adolescent self-harm behaviours in the ALSPAC birth cohort

IQ and adolescent self-harm behaviours in the ALSPAC birth cohort
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DOI:
10.1016/j.jad.2013.09.005
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发表时间:
2014-01-01
影响因子:
6.6
通讯作者:
Gunnell, David
Gunnell, David
中科院分区:
医学2区
文献类型:
--
作者:
Chang, Shu-Sen;Chen, Ying-Yeh;Gunnell, David

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背景资料:低智商与自杀和自杀企图的成年人的风险增加,但鲜为人知的是智商和方面的自杀/自我伤害behaviors.Methods:我们使用的数据从雅芳纵向研究的父母和孩子(ALSPAC),一个以人口为基础的前瞻性英国队列。二项和多项logistic回归模型被用来研究智商在8岁时测量的自杀相关的结果之间的4810青少年年龄16-17 years.Results:有一些证据表明,协会不同的男孩和女孩(p值之间的相互作用范围为0.06和025)。在男孩中,较高的智商与自杀想法(智商分数每增加10分的校正比值比=1.14,95%置信区间[CI] 1.01-1.28)和自杀计划(1.15,95% CI 0.93-1.43)的风险增加相关,尽管后一种关联的统计学证据有限。还有证据表明与非自杀性自残(124,95%CI 1.08-1.45)有关,但与自杀性自残(1.04,95%CI 0.86-1.25)无关。在女孩中,高智商与非自杀性自我伤害的风险增加有关(1.11,95%CI 1.02-1.22),但不包括自杀念头、自杀计划或自杀性自我伤害。局限性:失访和问卷无应答可能导致选择偏倚。结论:与之前关于成人智商与自杀相关性的研究相反,我们发现,高智商与男性和女性青少年非自杀性自我伤害的风险增加以及男性自杀想法的风险增加有关。智商与自我伤害的关联对于有自杀意图和没有自杀意图的自我伤害不同,这表明这些行为的病因可能不同。(C)© 2013 Elsevier B. V.版权所有
Background: Low IQ is associated with an increased risk of suicide and suicide attempt in adults, but less is known about the relationship between IQ and aspects of suicidal/self-harm behaviours in adolescence.Methods: We used data from the Avon Longitudinal Study of Parents and Children (ALSPAC), a population-based prospective UK cohort. Binomial and multinomial logistic regression models were used to examine the association of IQ measured at age 8 with suicide-related outcomes amongst 4810 adolescents aged 16-17 years.Results: There was some evidence that associations differed in boys and girls (p values for interaction ranged between 0.06 and 025). In boys higher IQ was associated with increased risk of suicidal thoughts (adjusted odds ratio per 10 point increase in IQ score=1.14, 95% Confidence Interval [CI] 1.01-1.28) and suicidal plans (1.15, 95% CI 0.93-1.43), although statistical evidence for the latter association was limited. There was also evidence for an association with non-suicidal self-harm (124, 95% CI 1.08-1.45) but not suicidal self-harm (1.04, 95% CI 0.86-1.25). In girls higher IQ was associated with increased risk of non-suicidal self-harm (1.11, 95% CI 1.02-1.22) but not suicidal thoughts, suicidal plans or suicidal self-harm.Limitations: Loss to follow up and questionnaire non-response may have led to selection bias.Conclusion: In contrast to previous studies of IQ-suicide associations in adults, we found that higher IQ was associated with an increased risk of non-suicidal self-harm in male and female adolescents and suicidal thoughts in males. Associations of IQ with self-harm differed for self-harm with and without suicidal intent, suggesting that the aetiology of these behaviours may differ. (C) 2013 Elsevier B.V. All rights reserved