Autism Spectrum Disorders and Low Mental Age: Diagnostic Stability and Developmental Outcomes in Early Childhood.
Autism Spectrum Disorders and Low Mental Age: Diagnostic Stability and Developmental Outcomes in Early Childhood.
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DOI：
10.1007/s10803-017-3278-y
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发表时间：
2017-12
影响因子：
3.9
通讯作者：
Fein DA
中科院分区：
文献类型：
--
作者：
Hinnebusch AJ;Miller LE;Fein DA
摘要一些自闭症谱系障碍（ASD）儿童表现出低智力年龄（Low-MA），这里定义为认知功能低于12个月。我们检查了ASD-低MA（n = 25），DSM-IV-TR自闭症障碍（n = 111）和DSM-IV-TRPDD-NOS（n = 82）儿童在2岁时的诊断，症状严重程度和发育，并在4岁时进行随访。我们预测，一些ASD低MA儿童在随访时仅表现出智力障碍，而不是ASD的症状，他们在两岁时的社交缺陷可归因于全面发育迟缓。相反，大多数ASD低MA儿童（96%）在随访时患有ASD，而最初诊断为自闭症障碍（86.5%）或PDD-NOS（73.2%）的儿童。在两次评估中，他们还表现出最小的发育进展和最高的症状严重程度。结果支持诊断ASD，即使在儿童功能低于12个月的水平。
Abstract Some children with Autism Spectrum Disorders (ASDs) exhibit low mental age (Low-MA), defined here as cognitive functioning below 12 months. We examined diagnosis, symptom severity, and development in children with ASD-Low MA (n = 25), DSM-IV-TR Autistic Disorder (n = 111), and DSM-IV-TRPDD-NOS (n = 82) at age two and follow-up at age four. We predicted that some ASD-Low MA children would demonstrate just intellectual impairment and not symptoms of an ASD on follow-up, with their social deficits at age two attributable to Global Developmental Delay. Instead, most ASD-Low MA children (96%) had an ASD at follow-up, compared to children with an initial diagnosis of Autistic Disorder (86.5%) or PDD-NOS (73.2%). They also showed the least developmental progress and highest symptom severity at both evaluations. Results support diagnosing ASDs even in children functioning below a 12-month level.
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影响因子：
3.9
作者：
Barton ML;Robins DL;Jashar D;Brennan L;Fein D
通讯作者：
Fein D
影响因子：
2.5
作者：
Eikeseth, Svein;Klintwall, Lars;Karlsson, Peter
通讯作者：
Karlsson, Peter
影响因子：
3.9
作者：
Lord, C;Risi, S;Rutter, M
通讯作者：
Rutter, M
DOI：
10.1111/j.1469-7610.1989.tb00269.x
发表时间：
1989-07-01
影响因子：
7.6
作者：
LORD, C;SCHOPLER, E
通讯作者：
SCHOPLER, E
影响因子：
7.6
作者：
Anderson, Deborah K.;Liang, Jessie W.;Lord, Catherine
通讯作者：
Lord, Catherine