Reliability and validity of two HIV/AIDS-specific quality of life instruments adapted for use in HIV-positive Zimbabweans

Reliability and validity of two HIV/AIDS-specific quality of life instruments adapted for use in HIV-positive Zimbabweans
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DOI:
10.1080/09540120802302574
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发表时间:
2009-01-01
影响因子:
1.7
通讯作者:
Holmes, William C.
Holmes, William C.
中科院分区:
医学4区
文献类型:
--
作者:
Taylor, Tonya N.;Dolezal, Curtis;Holmes, William C.

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我们试图评估艾滋病毒/艾滋病目标生活质量工具(HAT-QoL)和医疗结果研究艾滋病毒健康调查(MOS-HIV)的可靠性和结构效度,适用于津巴布韦讲绍纳语的农村地区。HAT-QoL和MOS-HIV被翻译并在文化上适应于Shona,并被用于400名hiv相关机会性感染患者的方便样本。评估HIV疾病严重程度和丧亲史。对HAT-QoL项目的因素分析产生了七个因素,这些因素几乎与美国样本报告的因素结构相同,这是当前HAT-QoL量表的基础。MOS-HIV量表的因子分析结果是单因素,而不是预期的双因素结构(生理和心理)。收敛效度评估和判别效度评估均证实,相似的Shona HAT-QoL和MOS-HIV维度存在相关性,不相似的Shona HAT-QoL和MOS-HIV维度不存在相关性。结构效度评估表明,总体而言,大多数Shona HAT-QoL和MOS-HIV维度捕获了预期的亚组差异。除一般健康知觉、认知功能和生活质量(QoL)项目的Shona MOS-HIV维度外。大多数适用于绍纳语的HAT-QoL和MOS-HIV维度的信度和效度表明,这两种工具可能对测量津巴布韦、莫桑比克、赞比亚和博茨瓦纳讲绍纳语的农村人口的QoL有用。
We sought to assess the reliability and construct validity of the HIV/AIDS-Targeted Quality of Life instrument (HAT-QoL) and the Medical Outcomes Study HIV Health Survey (MOS-HIV) adapted for use in Shona-speaking rural Zimbabwe. HAT-QoL and MOS-HIV were translated and culturally adapted into Shona, and administered to a convenience-sample of 400 patients with HIV-related opportunistic infections. HIV disease severity and bereavement history were assessed. Factor analysis of the HAT-QoL items produced seven factors that were nearly identical to the factor structure reported for an American sample that was the basis for the current HAT-QoL scales. Factor analysis of the MOS-HIV scales resulted in a single factor, not the expected two-factor structure (physical and mental). Convergent and discriminant validity assessments confirmed, in general, that similar Shona HAT-QoL and MOS-HIV dimensions were correlated and dissimilar ones not correlated. Construct validity assessments indicated that, on the whole, most Shona HAT-QoL and MOS-HIV dimensions were capturing anticipated subgroup differences. The exceptions were the Shona MOS-HIV dimensions of general health perceptions, cognitive function, and the quality of life (QoL) item. The reliability and validity of most Shona-adapted HAT-QoL and MOS-HIV dimensions suggest that both instruments are likely useful in measuring the QoL of rural, Shona-speaking populations in Zimbabwe, Mozambique, Zambia, and Botswana.