The surface morphology of embryonic and adult chick lens-fiber cells.
The surface morphology of embryonic and adult chick lens-fiber cells.
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胚胎和成年鸡晶状体纤维细胞的表面形态。
DOI：
10.1002/aja.1001590406
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发表时间：
1980
期刊：
影响因子：
--
通讯作者：
H. Maisel
中科院分区：
文献类型：
--
作者：
J. Kuszak;J. Alcala;H. Maisel
通过扫描电子显微镜研究了胚胎和成年鸡晶状体中晶状体纤维的表面形态。当伸长的上皮细胞进入终末分化状态时，它们会产生许多互连相邻纤维的细胞过程。互锁装置采用短杆上的球体、舌状翼片和指状突起的形状，分别适合相邻纤维的形状互补的插座、印记和指纹。包含超过 50% 的纤维细胞膜的间隙连接可用作超微结构联锁装置。联锁装置和间隙连接可能是维持纤维秩序所必需的——这是透镜透明度的关键要求。随着成熟度的增加，纤维及其联锁装置的均匀形态消失。年轻的均匀形状纤维细胞的高度重复有序排列可最大限度地减少大颗粒散射。这项研究的结果表明，晚期成熟的鸡纤维的均匀形状和秩序逐渐丧失。这种晶状体发育现象可能是其他物种（例如人类）老化晶状体中光散射增加的基础。
The surface morphology of lens fibers in embryonic and adult chicken lenses has been studied by scanning electron microscopy. As the elongating epithelial cells enter into a state of terminal differentiation they elaborate a number of cellular processes interconnecting neighboring fibers. The interlocking devices take the shapes of balls on a short stalk, tonguelike flaps, and fingerlike processes that fit into complementarily shaped sockets, imprints, and fingerprints, respectively, of adjoining fibers. Gap junctions comprising more than 50% of the fiber-cell membrane may serve as ultrastructural interlocking devices. The interlocking devices and gap junctions are probably necessary to maintain fiber order--a critical requirement for lens transparency. With increase maturation, the uniform morphology of the fibers and their interlocking devices is lost. The highly repetitive ordered alignment of young uniformly shaped fiber cells acts to minimize large-particle scatter. The results of this study show a progressive loss of uniform shape and order in chicken fibers of advanced maturity. This phenomenon of lens development may be the basis for the increase in light scattering seen in aged lenses of other species such as man.