Preconceptional cystic fibrosis carrier screening:: Attitudes and intentions of the target population

Preconceptional cystic fibrosis carrier screening:: Attitudes and intentions of the target population
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DOI:
10.1089/gte.2004.8.80
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发表时间:
2004-06-01
期刊:
GENETIC TESTING
影响因子:
--
通讯作者:
Ten Kate, LP
Ten Kate, LP
中科院分区:
其他
文献类型:
--
作者:
Poppelaars, FAM;Henneman, L;Ten Kate, LP

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本研究的目的是评估个人计划怀孕的态度和意图方面的孕前囊性纤维化(CF)载体筛查,并确定与积极和消极/中立的意图有测试相关的因素。以问卷为基础,对303对新婚夫妇(606人)进行了分层随机抽样调查。在符合条件的个体中,70%(n = 380)参与了研究。在受访者中,73%的人对常规提供的孕前CF携带者筛查持积极态度,56%的人有意参加筛查计划。一个积极的意图,有测试与高感知预期的遗憾,预期的先入为主的行为,高感知的压力,从专家,高感知的后果的测试结果,低感知的障碍,和低感知的负面后果的家庭成员。这些结果表明,常规孕前CF载体筛查的提供将导致大量接受夫妇计划怀孕。确定了与意图相关的几个变量。
The aim of this study was to assess the attitudes and intentions of individuals planning a pregnancy with regard to preconceptional cystic fibrosis (CF) carrier screening and to determine factors associated with a positive and negative/neutral intention to have the test. A survey, based on a questionnaire, was conducted among a stratified random sample of 303 recently married couples (606 individuals). Of the eligible individuals, 70% (n = 380) participated. Of the respondents, 73% had a positive attitude toward a routine offer of preconceptional CF carrier screening, and 56% had the intention to participate in a screening program. A positive intention to have the test was associated with high perceived anticipation of regret, intended preconceptional behavior, high perceived pressure from experts, high perceived consequences of the test results, low perceived barriers, and low perceived negative consequences for family members. These results suggest that the offer of routine preconceptional CF carrier screening would lead to substantial acceptance among couples planning a pregnancy. Several variables related with intention were identified.