Separation of amnion from choriodecidua is an integral event to the rupture of normal term fetal membranes and constitutes a significant component of the work required
Separation of amnion from choriodecidua is an integral event to the rupture of normal term fetal membranes and constitutes a significant component of the work required
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DOI：
10.1016/j.ajog.2005.06.083
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发表时间：
2006-01-01
影响因子：
9.8
通讯作者：
Moore, JJ
中科院分区：
文献类型：
--
作者：
Arikat, S;Novince, RW;Moore, JJ
目的：本研究旨在确定胎膜（FM）破裂过程中发生的事件顺序，并比较完整的FM与其分离的单个成分（羊膜和蜕膜）的生物物理特性。研究设计：FM的物理特性是通过电脑化的，特别适应的，工业的，强度测试设备和破裂顺序（体外）视频记录来确定的。将分离的单个FM成分的性质与重新近似的成分和完整的FM成分的性质进行比较。结果：调频断裂的顺序为：(1)调频构件在载荷作用下一起拉伸；(2)羊膜与蜕毛膜分离；(3)蜕膜破裂；(4)羊膜进一步非弹性膨胀；(5)羊膜破裂。在所有测试的FMs中，羊膜比蜕毛膜更坚固、更硬、更有韧性。破裂分离的FM组件（羊膜+蜕膜绒毛膜）或重新接近的组件所需的工作量明显少于完整的FM。结论：羊膜与蜕膜分离是足月羊膜破裂的一部分。由于这种分离，FMs明显变弱。(c) 2006 Mosby, Inc。版权所有。
Objective: This study was undertaken to determine the sequence of events that occur during fetal membrane (FM) rupture and to compare the biophysical properties of intact FM with its separated individual components (amnion and choriodecidua).Study design: FM physical properties were determined with Computerized, specially adapted, industrial, strength testing equipment and the rupture sequence (in vitro) video documented. Separated individual FM component properties were compared with those of reapproximated components, and of intact FMs.Results: The sequence of FM rupture was (1) FM components stretch together under load; (2) amnion separates from choriodecidua; (3) choriodecidua ruptures; (4) amnion distends further, nonelastically; and (5) amnion ruptures. In all FMs tested, amnion was stronger, stiffer, and more ductile than choriodecidua. The sum of work required to rupture separated FM components (amnion + choriodecidua), or reapproximated components, was significantly less than that of intact FMs.Conclusion: Separation of amnion from choriodecidua occurs as part of normal term FM rupture. FMs become significantly weaker as a result Of this separation. (c) 2006 Mosby, Inc. All rights reserved.