Molecular analysis of FRIGIDA, a major determinant of natural variation in Arabidopsis flowering time
Molecular analysis of FRIGIDA, a major determinant of natural variation in Arabidopsis flowering time
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DOI：
10.1126/science.290.5490.344
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发表时间：
2000-10-13
期刊：
影响因子：
56.9
通讯作者：
Dean, C
中科院分区：
文献类型：
--
作者：
Johanson, U;West, J;Dean, C
春化作用，即长时间的低温加速开花，使许多植物能在春天开花。在拟南芥中，FRIGIDA（FRI）基因座的等位基因变异是开花时间自然变异的主要决定因素。FRI的显性等位基因赋予晚开花，这是逆转春化早熟。我们克隆了FRI基因，并分析了其等位变异的分子基础。大多数早花生态型都携带FRI基因，该基因含有两种不同的缺失之一，破坏了开放阅读框架。因此，FRI的功能丧失突变为许多早花生态型的进化提供了基础。
Vernalization, the acceleration of flowering by a long period of cold temperature, ensures that many plants overwinter vegetatively and flower in spring. In Arabidopsis, allelic variation at the FRIGIDA (FRI) locus is a major determinant of natural variation in flowering time. Dominant alleles of FRI confer Late flowering, which is reversed to earliness by vernalization. We cloned FRI and analyzed the molecular basis of the allelic variation, Most of the early-flowering ecotypes analyzed carry FRI alleles containing one of two different deletions that disrupt the open reading frame. Loss-of-function mutations at FRI have thus provided the basis for the evolution of many early-flowering ecotypes.