A Method for Generation and Normalization of Katakana Variant Notations
A Method for Generation and Normalization of Katakana Variant Notations
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片假名变体符号的生成和规范化方法
DOI：
10.1016/j.jff.2018.11.020
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发表时间：
1993
影响因子：
5.6
通讯作者：
青江 順一
中科院分区：
文献类型：
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作者：
獅々堀正幹;青江 順一
在动物中显示，卵蛋白水解物NWT-03改善内皮功能。我们设计了一项人体交叉研究，以评估5g/d NWT-03在40名超重和肥胖的糖耐量受损或2型糖尿病受试者中的急性（2小时）和短期（2天）效应。（时间点0; t0）和摄入后120分钟（t120），以及第3天（t120），脉搏波速度，增强指数，测量心率和血压，并采集血液用于分析代谢参数（血脂、葡萄糖和胰岛素）。计算急性和短期效应。在食用NWT-03期间，颈动脉-桡动脉PWV（短期）、AIx（急性）、三酰甘油（短期）、葡萄糖（急性）和胰岛素（急性）降低，而HDL胆固醇（短期）显著升高。鸡蛋蛋白水解物NWT-03是IGT和T2 DM的潜在功能性食品成分。cr-PWV的改善是否是通过对代谢的影响以及长期益处介导的，需要进一步研究。
It was shown in animals that the egg protein-hydrolysate NWT-03 improves endothelial function. We designed a human crossover study to assess acute (2 h) and short-term (2 days) effects of 5 g/d NWT-03 in 40 overweight and obese subjects with impaired glucose-tolerance or type-2 diabetes.At day 1, both fasting (time point 0;t0) and 120 min after intake (t120), and day 3 (t120), pulse-wave velocity, augmentation index, heart rate and blood pressure were measured and blood was sampled for analysis of metabolic parameters (serum lipids, glucose and insulin). Acute and short-term effects were calculated.Carotid-radial PWV (short-term), AIx (acute), triacylglycerol (short-term), glucose (acute), and insulin (acute) decreased, while HDL cholesterol (short-term) increased significantly during NWT-03 consumption.The egg protein-hydrolysate NWT-03 is a potential functional food ingredient in IGT and T2DM. Whether the improvement in cr-PWV is mediated through effects on metabolism as well as long-term benefits warrants further study.