The changing pattern of laryngeal tuberculosis
The changing pattern of laryngeal tuberculosis
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喉结核的变化规律
DOI：
10.1017/s0022215100090861
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发表时间：
1981
期刊：
影响因子：
--
通讯作者：
Horne
中科院分区：
文献类型：
--
作者：
B. Hunter;J. W. Millar;A. A.J.;Wightman;W. N.;Horne
总结喉结核现在是一种罕见的疾病在英国。报告了一系列10例病例。与化疗前相比，当这种疾病与晚期空洞性肺结核相关并且具有高度传染性时，它现在以类似于喉癌的方式出现，除了疼痛性吞咽困难是一个突出的症状。所有这些患者都应进行胸部X光检查，作为初步调查的一部分。痰液在直接片上几乎总是结核杆菌阳性。如果怀疑是癌，直接喉镜检查和活组织检查是必要的。疾病模式的改变可能是由于喉现在通常通过血源性传播而不是通过沿着气道直接传播。喉结核现在并不比肺结核更具传染性，并且对抗结核化疗反应良好。如果联合使用皮质类固醇，症状在三周内完全消失。
Summary Laryngeal tuberculosis is now an uncommon disease in the United Kingdom. A series of ten cases is reported. In contrast to the pre-chemotherapy era, when the disease was associated with advanced cavitated pulmonary tuberculosis and was highly infectious, it now presents in a manner similar to laryngeal carcinoma except that painful dysphagia is a prominent symptom. All such patients should have a chest X-ray carried out as part of their initial investigation. Sputum is almost always positive for tubercle bacilli on direct films. Direct laryngoscopy and biopsy are necessary if a carcinoma is suspected. The change of pattern of the disease may be due to the fact that the larynx now usually becomes involved by haematogenous spread rather than by direct spread along the airways. Laryngeal tuberculosis is now no more infectious than pulmonary tuberculosis, and responds well to antituberculous chemotherapy. Symptoms resolve completely within three weeks if corticosteroids are given in combination.