A new approach for neurological evaluation of infants in resource-poor settings
A new approach for neurological evaluation of infants in resource-poor settings
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DOI：
10.1179/027249302125002029
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发表时间：
2002-12-01
影响因子：
--
通讯作者：
Dubowitz, L
中科院分区：
文献类型：
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作者：
Haataja, L;McGready, R;Dubowitz, L
评估发展中国家婴儿神经发育的研究很少，因为没有合适的标准化测试可供在受限环境下现场使用。我们描述了两种简单评估的发展和应用。首先，我们的目标是开发一种适合于评估由感染、药物或毒素等多种影响引起的急性神经功能障碍的测试。这项测试(肖克罗神经学测试)针对的是9到36个月的婴儿。第二项测试(Shoklo发育测试)的目的不仅是跟踪急性期最初测试的体征的演变，而且还评估可能由相同事件引起的后来的神经发育后遗症。后一种测试适用于3至12个月大的婴儿。这两种测试都可以在非最佳条件下轻松执行。这些检查是在克伦难民营的一群婴儿中进行测试的，并由卫生工作者在农村环境下进行，经过适当的培训。为了验证这些测试，我们还对伦敦的一群婴儿进行了测试。格里菲斯发育量表被应用于相同的婴儿，Shoklo神经学和Shoklo发育测试都表明与这一标准化的神经发育评估有很好的相关性。
Research assessing the neurological development of infants in developing countries is scanty as no suitable standardised tests are available for field-use in constrained circumstances. We describe the development and application of two simple assessments. Firstly, we aimed to develop a test suitable for assessing acute neurological disturbances caused by such diverse effects as infections, drugs or toxins. This test (Shoklo Neurological Test) is aimed at infants between 9 and 36 months. The second test (Shoklo Developmental Test) is aimed not only to follow the evolution of the signs tested initially in the acute phase but also to evaluate later neurodevelopmental sequelae which might be caused by the same events. The latter test is suitable for infants aged from 3 to 12 months. Both tests can be performed easily in non-optimal conditions. The examinations were tested in a cohort of infants from a Karen refugee camp and administered in a rural setting by health workers, after appropriate training. In order to validate the tests we also applied them to a cohort of London infants. The Griffiths Developmental Scales were applied in the same infants and both the Shoklo Neurological and the Shoklo Developmental Tests showed good correlation with this standardised neurodevelopmental assessment.